Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers
Poor neural speech discrimination has been connected to dyslexia, and may represent phonological processing deficits that are hypothesized to be the main cause for reading impairments. Thus far, neural speech discrimination impairments have rarely been investigated in adult dyslexics, and even less...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-08-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844020314638 |
| _version_ | 1818610041092046848 |
|---|---|
| author | A. Thiede L. Parkkonen P. Virtala M. Laasonen J.P. Mäkelä T. Kujala |
| author_facet | A. Thiede L. Parkkonen P. Virtala M. Laasonen J.P. Mäkelä T. Kujala |
| author_sort | A. Thiede |
| collection | DOAJ |
| description | Poor neural speech discrimination has been connected to dyslexia, and may represent phonological processing deficits that are hypothesized to be the main cause for reading impairments. Thus far, neural speech discrimination impairments have rarely been investigated in adult dyslexics, and even less by examining sources of neuromagnetic responses. We compared neuromagnetic speech discrimination in dyslexic and typical readers with mismatch fields (MMF) and determined the associations between MMFs and reading-related skills. We expected weak and atypically lateralized MMFs in dyslexic readers, and positive associations between reading-related skills and MMF strength. MMFs were recorded to a repeating pseudoword /ta-ta/ with occasional changes in vowel identity, duration, or syllable frequency from 43 adults, 21 with confirmed dyslexia. Phonetic (vowel and duration) changes elicited left-lateralized MMFs in the auditory cortices. Contrary to our hypothesis, MMF source strengths or lateralization did not differ between groups. However, better verbal working memory was associated with stronger left-hemispheric MMFs to duration changes across groups, and better reading was associated with stronger right-hemispheric late MMFs across speech-sound changes in dyslexic readers. This suggests a link between neural speech processing and reading-related skills, in line with previous work. Furthermore, our findings suggest a right-hemispheric compensatory mechanism for language processing in dyslexia. The results obtained promote the use of MMFs in investigating reading-related brain processes. |
| first_indexed | 2024-12-16T15:08:07Z |
| format | Article |
| id | doaj.art-d7ba394137a14c8da7ef6b6befc1821a |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-16T15:08:07Z |
| publishDate | 2020-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-d7ba394137a14c8da7ef6b6befc1821a2022-12-21T22:27:03ZengElsevierHeliyon2405-84402020-08-0168e04619Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readersA. Thiede0L. Parkkonen1P. Virtala2M. Laasonen3J.P. Mäkelä4T. Kujala5Cognitive Brain Research Unit, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland; Corresponding author.Department of Neuroscience and Biomedical Engineering, School of Science, Aalto University, Finland; Aalto Neuroimaging, Aalto University, FinlandCognitive Brain Research Unit, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, FinlandDepartment of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland; Department of Phoniatrics, Helsinki University Hospital, FinlandBioMag Laboratory, HUS Medical Imaging Center, Helsinki University Central Hospital, FinlandCognitive Brain Research Unit, Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, FinlandPoor neural speech discrimination has been connected to dyslexia, and may represent phonological processing deficits that are hypothesized to be the main cause for reading impairments. Thus far, neural speech discrimination impairments have rarely been investigated in adult dyslexics, and even less by examining sources of neuromagnetic responses. We compared neuromagnetic speech discrimination in dyslexic and typical readers with mismatch fields (MMF) and determined the associations between MMFs and reading-related skills. We expected weak and atypically lateralized MMFs in dyslexic readers, and positive associations between reading-related skills and MMF strength. MMFs were recorded to a repeating pseudoword /ta-ta/ with occasional changes in vowel identity, duration, or syllable frequency from 43 adults, 21 with confirmed dyslexia. Phonetic (vowel and duration) changes elicited left-lateralized MMFs in the auditory cortices. Contrary to our hypothesis, MMF source strengths or lateralization did not differ between groups. However, better verbal working memory was associated with stronger left-hemispheric MMFs to duration changes across groups, and better reading was associated with stronger right-hemispheric late MMFs across speech-sound changes in dyslexic readers. This suggests a link between neural speech processing and reading-related skills, in line with previous work. Furthermore, our findings suggest a right-hemispheric compensatory mechanism for language processing in dyslexia. The results obtained promote the use of MMFs in investigating reading-related brain processes.http://www.sciencedirect.com/science/article/pii/S2405844020314638DyslexiaMagnetoencephalography (MEG)Speech processingMismatch field (MMF)Reading skillsVerbal working memory |
| spellingShingle | A. Thiede L. Parkkonen P. Virtala M. Laasonen J.P. Mäkelä T. Kujala Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers Heliyon Dyslexia Magnetoencephalography (MEG) Speech processing Mismatch field (MMF) Reading skills Verbal working memory |
| title | Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers |
| title_full | Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers |
| title_fullStr | Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers |
| title_full_unstemmed | Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers |
| title_short | Neuromagnetic speech discrimination responses are associated with reading-related skills in dyslexic and typical readers |
| title_sort | neuromagnetic speech discrimination responses are associated with reading related skills in dyslexic and typical readers |
| topic | Dyslexia Magnetoencephalography (MEG) Speech processing Mismatch field (MMF) Reading skills Verbal working memory |
| url | http://www.sciencedirect.com/science/article/pii/S2405844020314638 |
| work_keys_str_mv | AT athiede neuromagneticspeechdiscriminationresponsesareassociatedwithreadingrelatedskillsindyslexicandtypicalreaders AT lparkkonen neuromagneticspeechdiscriminationresponsesareassociatedwithreadingrelatedskillsindyslexicandtypicalreaders AT pvirtala neuromagneticspeechdiscriminationresponsesareassociatedwithreadingrelatedskillsindyslexicandtypicalreaders AT mlaasonen neuromagneticspeechdiscriminationresponsesareassociatedwithreadingrelatedskillsindyslexicandtypicalreaders AT jpmakela neuromagneticspeechdiscriminationresponsesareassociatedwithreadingrelatedskillsindyslexicandtypicalreaders AT tkujala neuromagneticspeechdiscriminationresponsesareassociatedwithreadingrelatedskillsindyslexicandtypicalreaders |