An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals
Serotonin (5-HT) plays many important roles in reward, punishment, patience and beyond, and optogenetic stimulation of 5-HT neurons has not crisply parsed them. The authors report a novel analysis of a reward-based decision-making experiment, and show that 5-HT stimulation increases the learning rat...
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Format: | Article |
Language: | English |
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Nature Portfolio
2018-06-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-04840-2 |
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author | Kiyohito Iigaya Madalena S. Fonseca Masayoshi Murakami Zachary F. Mainen Peter Dayan |
author_facet | Kiyohito Iigaya Madalena S. Fonseca Masayoshi Murakami Zachary F. Mainen Peter Dayan |
author_sort | Kiyohito Iigaya |
collection | DOAJ |
description | Serotonin (5-HT) plays many important roles in reward, punishment, patience and beyond, and optogenetic stimulation of 5-HT neurons has not crisply parsed them. The authors report a novel analysis of a reward-based decision-making experiment, and show that 5-HT stimulation increases the learning rate, but only on a select subset of choices. |
first_indexed | 2024-12-20T20:10:29Z |
format | Article |
id | doaj.art-d7bc3de7103a474cb12f9bf2b53a8a92 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-20T20:10:29Z |
publishDate | 2018-06-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-d7bc3de7103a474cb12f9bf2b53a8a922022-12-21T19:27:49ZengNature PortfolioNature Communications2041-17232018-06-019111010.1038/s41467-018-04840-2An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervalsKiyohito Iigaya0Madalena S. Fonseca1Masayoshi Murakami2Zachary F. Mainen3Peter Dayan4Gatsby Computational Neuroscience Unit, University College LondonChampalimaud Research, Champalimaud Centre for the UnknownChampalimaud Research, Champalimaud Centre for the UnknownChampalimaud Research, Champalimaud Centre for the UnknownGatsby Computational Neuroscience Unit, University College LondonSerotonin (5-HT) plays many important roles in reward, punishment, patience and beyond, and optogenetic stimulation of 5-HT neurons has not crisply parsed them. The authors report a novel analysis of a reward-based decision-making experiment, and show that 5-HT stimulation increases the learning rate, but only on a select subset of choices.https://doi.org/10.1038/s41467-018-04840-2 |
spellingShingle | Kiyohito Iigaya Madalena S. Fonseca Masayoshi Murakami Zachary F. Mainen Peter Dayan An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals Nature Communications |
title | An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals |
title_full | An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals |
title_fullStr | An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals |
title_full_unstemmed | An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals |
title_short | An effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals |
title_sort | effect of serotonergic stimulation on learning rates for rewards apparent after long intertrial intervals |
url | https://doi.org/10.1038/s41467-018-04840-2 |
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