Establishment of hKDR+/+ Humanized and Rag1-/- Gene Knockout Double Genetically Modified Mouse Model

Establishment of hKDR+/+ Humanized and Rag1-/- Gene Knockout Double Genetically Modified Mouse Model

ObjectiveThrough improving the potential of vascular endothelial growth factor receptor (VEGFR)-humanized mouse model (hKDR+/+) with C57BL/6N background to allow the growth of different mouse tumor cell lines, to establish novel tumor-bearing mouse models which can support in vivo tumorigenesis of d...

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Bibliographic Details
Main Authors: LIU Susu, WU Yong, CAO Yuan, ZHAO Haoyang, ZHAI Shijie, SUN Xiaowei, LI Linli, FAN Changfa
Format: Article
Language:zho
Published: Editorial Office of Laboratory Animal and Comparative Medicine 2023-04-01
Series:Shiyan dongwu yu bijiao yixue
Subjects:
hkdr+/+ humanized mice
rag1-/- knockout mice
vegfr target
antibodies
tumor
Online Access:https://www.slarc.org.cn/dwyx/CN/10.12300/j.issn.1674-5817.2022.154

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