An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, and liver transplantation is usually curative. HCC recurrences are rare after curative treatment options, although they are prevalent depending on various risk factors. We present a 71-year-old female patient with an unusual...

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Main Authors: Patrick Gidley, Anand Patel, Guliz A. Barkan, Anugayathri Jawahar
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-07-01
Series:Indian Journal of Radiology and Imaging
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1767694
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author Patrick Gidley
Anand Patel
Guliz A. Barkan
Anugayathri Jawahar
author_facet Patrick Gidley
Anand Patel
Guliz A. Barkan
Anugayathri Jawahar
author_sort Patrick Gidley
collection DOAJ
description Hepatocellular carcinoma (HCC) is the most common primary liver malignancy, and liver transplantation is usually curative. HCC recurrences are rare after curative treatment options, although they are prevalent depending on various risk factors. We present a 71-year-old female patient with an unusual pattern of disease progression following a curative liver transplant with a metastatic presentation in the absence of alpha-fetoprotein elevation after 3 years of disease-free clinical presentation. We present this case to emphasize the importance of intermittent cross-sectional imaging in addition to ultrasound screening in HCC surveillance.
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spelling doaj.art-d7bed25a99ec4177acf387323ab9c80d2023-06-23T23:34:27ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Radiology and Imaging0971-30261998-38082023-07-01330342042310.1055/s-0043-1767694An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver TransplantPatrick Gidley0Anand Patel1Guliz A. Barkan2Anugayathri Jawahar3Department of Radiology, Loyola University Medical Center, Maywood, Illinois, United StatesLoyola University Chicago- Stritch School of Medicine, Maywood, Illinois, United StatesDepartment of Pathology, Loyola University Medical Center, Maywood, Illinois, United StatesDepartment of Radiology, Northwestern University- Feinberg School of Medicine, Chicago, Illinois, United StatesHepatocellular carcinoma (HCC) is the most common primary liver malignancy, and liver transplantation is usually curative. HCC recurrences are rare after curative treatment options, although they are prevalent depending on various risk factors. We present a 71-year-old female patient with an unusual pattern of disease progression following a curative liver transplant with a metastatic presentation in the absence of alpha-fetoprotein elevation after 3 years of disease-free clinical presentation. We present this case to emphasize the importance of intermittent cross-sectional imaging in addition to ultrasound screening in HCC surveillance.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1767694hepatocellular carcinomahcc metastasespancreatic metastasesgastric metastasespost-liver transplant metastases
spellingShingle Patrick Gidley
Anand Patel
Guliz A. Barkan
Anugayathri Jawahar
An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant
Indian Journal of Radiology and Imaging
hepatocellular carcinoma
hcc metastases
pancreatic metastases
gastric metastases
post-liver transplant metastases
title An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant
title_full An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant
title_fullStr An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant
title_full_unstemmed An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant
title_short An Atypical Presentation of Hepatocellular Carcinoma with Multisite Metastasis following a Curative Liver Transplant
title_sort atypical presentation of hepatocellular carcinoma with multisite metastasis following a curative liver transplant
topic hepatocellular carcinoma
hcc metastases
pancreatic metastases
gastric metastases
post-liver transplant metastases
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1767694
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