Identification of a Goat Intersexuality-Associated Novel Variant Through Genome-Wide Resequencing and Hi-C

Identification of a Goat Intersexuality-Associated Novel Variant Through Genome-Wide Resequencing and Hi-C

Background: Polled intersex syndrome (PIS) leads to reproductive disorders in goats and exerts a heavy influence on goat breeding. Since 2001, the core variant of an 11.7 kb deletion at ~129 Mb on chromosome 1 (CHI1) has been widely used as a genetic diagnostic criterion. In 2020, a ~0.48 Mb inserti...

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Bibliographic Details
Main Authors: Guang-Xin E, Dong-Ke Zhou, Zhu-Qing Zheng, Bai-Gao Yang, Xiang-Long Li, Lan-Hui Li, Rong-Yan Zhou, Wen-Hui Nai, Xun-Ping Jiang, Jia-Hua Zhang, Qiong-Hua Hong, Yue-Hui Ma, Ming-Xing Chu, Hui-Jiang Gao, Yong-Ju Zhao, Xing-Hai Duan, Yong-Meng He, Ri-Su Na, Yan-Guo Han, Yan Zeng, Yu Jiang, Yong-Fu Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
intersexuality
genome-wide selection
Hi-C
copy number variant
translocation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.616743/full

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