APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction

Apolipoprotein E4 (ApoE4) is the strongest genetic risk factor for late onset Alzheimer’s Disease (AD), and is associated with impairments in cerebral metabolism and cerebrovascular function. A substantial body of literature now points to E4 as a driver of multiple impairments seen in AD, including...

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Bibliographic Details
Main Authors: Jason A. Brandon, Brandon C. Farmer, Holden C. Williams, Lance A. Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
ApoE
apolipoprotein E
cerebral
metabolism
brain
imaging
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00180/full

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