Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology

Case series summary Two cats were presented for further investigation of respiratory signs. One cat had a history of a cough and the other, tachypnoea. In each case, thoracic CT was performed, which revealed a generalised marked reticular pattern in the first cat and focal consolidation of the right...

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Main Authors: Eleanor C Duffy, Sally Griffin, Erin M O’Connell, Jeremy R Mortier
Format: Article
Language:English
Published: SAGE Publishing 2020-11-01
Series:Journal of Feline Medicine and Surgery Open Reports
Online Access:https://doi.org/10.1177/2055116920968723
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author Eleanor C Duffy
Sally Griffin
Erin M O’Connell
Jeremy R Mortier
author_facet Eleanor C Duffy
Sally Griffin
Erin M O’Connell
Jeremy R Mortier
author_sort Eleanor C Duffy
collection DOAJ
description Case series summary Two cats were presented for further investigation of respiratory signs. One cat had a history of a cough and the other, tachypnoea. In each case, thoracic CT was performed, which revealed a generalised marked reticular pattern in the first cat and focal consolidation of the right caudal lung lobe in the second cat. The first cat was euthanased following completion of the imaging study and a post-mortem examination was performed. The second cat underwent surgical excision of the abnormal lung lobe and survived for 4 years after diagnosis. Histopathology performed on lung tissue removed from each cat was consistent with pulmonary fibrosis. Relevance and novel information This small case series adds to the existing literature and highlights the heterogeneous clinical course and variable appearance of pulmonary fibrosis on CT of affected cats. These cases provide evidence that pulmonary fibrosis in cats incorporates a wide spectrum of fibrotic lung disease and demonstrates the possibility for prolonged survival following diagnosis where disease is localised and amenable to surgical resection.
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spelling doaj.art-d7c7622618064748a53f598bb863f5032022-12-22T00:14:43ZengSAGE PublishingJournal of Feline Medicine and Surgery Open Reports2055-11692020-11-01610.1177/2055116920968723Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiologyEleanor C Duffy0Sally Griffin1Erin M O’Connell2Jeremy R Mortier3Institute of Veterinary Science, University of Liverpool, Neston, UKDiagnostic Imaging Department, Willows Veterinary Centre & Referral Service, Solihull, UKInstitute of Veterinary Science, University of Liverpool, Neston, UKInstitute of Veterinary Science, University of Liverpool, Neston, UKCase series summary Two cats were presented for further investigation of respiratory signs. One cat had a history of a cough and the other, tachypnoea. In each case, thoracic CT was performed, which revealed a generalised marked reticular pattern in the first cat and focal consolidation of the right caudal lung lobe in the second cat. The first cat was euthanased following completion of the imaging study and a post-mortem examination was performed. The second cat underwent surgical excision of the abnormal lung lobe and survived for 4 years after diagnosis. Histopathology performed on lung tissue removed from each cat was consistent with pulmonary fibrosis. Relevance and novel information This small case series adds to the existing literature and highlights the heterogeneous clinical course and variable appearance of pulmonary fibrosis on CT of affected cats. These cases provide evidence that pulmonary fibrosis in cats incorporates a wide spectrum of fibrotic lung disease and demonstrates the possibility for prolonged survival following diagnosis where disease is localised and amenable to surgical resection.https://doi.org/10.1177/2055116920968723
spellingShingle Eleanor C Duffy
Sally Griffin
Erin M O’Connell
Jeremy R Mortier
Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology
Journal of Feline Medicine and Surgery Open Reports
title Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology
title_full Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology
title_fullStr Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology
title_full_unstemmed Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology
title_short Clinical, computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology
title_sort clinical computed tomographic and histopathological findings in two cats with pulmonary fibrosis of unknown aetiology
url https://doi.org/10.1177/2055116920968723
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