Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS
A broad range of similarities between HIV-1 gp120 and human proteins-especially those participating in immune responses-highlight gp120 as a pleiotropic protein which can influence many important functions of the human immune system. The molecular mimicry that serves to the human immunodeficiency vi...
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| Format: | Article |
| Language: | English |
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Institute of Oncology, Sremska Kamenica, Serbia
2005-01-01
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| Series: | Archive of Oncology |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0354-7310/2005/0354-73100504126V.pdf |
| _version_ | 1818778534266535936 |
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| author | Veljković Nevena V. |
| author_facet | Veljković Nevena V. |
| author_sort | Veljković Nevena V. |
| collection | DOAJ |
| description | A broad range of similarities between HIV-1 gp120 and human proteins-especially those participating in immune responses-highlight gp120 as a pleiotropic protein which can influence many important functions of the human immune system. The molecular mimicry that serves to the human immunodeficiency virus as potent destructive arms against immune system could be the weak point we are in search of over decades. Examples involving sequence and informational similarities of HIV-1 gp120 and immunerelated host cell proteins important for prevention and treatment of HIV infection are presented. . |
| first_indexed | 2024-12-18T11:46:15Z |
| format | Article |
| id | doaj.art-d7c7653dbdb241adabdbd8750028a33b |
| institution | Directory Open Access Journal |
| issn | 0354-7310 |
| language | English |
| last_indexed | 2024-12-18T11:46:15Z |
| publishDate | 2005-01-01 |
| publisher | Institute of Oncology, Sremska Kamenica, Serbia |
| record_format | Article |
| series | Archive of Oncology |
| spelling | doaj.art-d7c7653dbdb241adabdbd8750028a33b2022-12-21T21:09:17ZengInstitute of Oncology, Sremska Kamenica, SerbiaArchive of Oncology0354-73102005-01-01133-412613010.2298/AOO0504126VMolecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDSVeljković Nevena V.A broad range of similarities between HIV-1 gp120 and human proteins-especially those participating in immune responses-highlight gp120 as a pleiotropic protein which can influence many important functions of the human immune system. The molecular mimicry that serves to the human immunodeficiency virus as potent destructive arms against immune system could be the weak point we are in search of over decades. Examples involving sequence and informational similarities of HIV-1 gp120 and immunerelated host cell proteins important for prevention and treatment of HIV infection are presented. .http://www.doiserbia.nb.rs/img/doi/0354-7310/2005/0354-73100504126V.pdfmolecular mimicryHIV envelope protein gp120acquired immunodeficiency syndromeAIDSvaccinestherapyinvestigationalvasoactive intestinal peptidecross reactionsantibodiesviral |
| spellingShingle | Veljković Nevena V. Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS Archive of Oncology molecular mimicry HIV envelope protein gp120 acquired immunodeficiency syndrome AIDS vaccines therapy investigational vasoactive intestinal peptide cross reactions antibodies viral |
| title | Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS |
| title_full | Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS |
| title_fullStr | Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS |
| title_full_unstemmed | Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS |
| title_short | Molecular mimicry of HIV gp120: Possible implications on prevention and therapy of AIDS |
| title_sort | molecular mimicry of hiv gp120 possible implications on prevention and therapy of aids |
| topic | molecular mimicry HIV envelope protein gp120 acquired immunodeficiency syndrome AIDS vaccines therapy investigational vasoactive intestinal peptide cross reactions antibodies viral |
| url | http://www.doiserbia.nb.rs/img/doi/0354-7310/2005/0354-73100504126V.pdf |
| work_keys_str_mv | AT veljkovicnevenav molecularmimicryofhivgp120possibleimplicationsonpreventionandtherapyofaids |