The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C Intake
Polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), α-linolenic acid (ALA), or linoleic acid (LA), have a particular role in counteracting cardiovascular diseases. They may regulate antioxidant potential and inflammatory reactions. Little is known whether ot...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/12/2/267 |
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| author | Anna Gawron-Skarbek Agnieszka Guligowska Anna Prymont-Przymińska Dariusz Nowak Tomasz Kostka |
| author_facet | Anna Gawron-Skarbek Agnieszka Guligowska Anna Prymont-Przymińska Dariusz Nowak Tomasz Kostka |
| author_sort | Anna Gawron-Skarbek |
| collection | DOAJ |
| description | Polyunsaturated fatty acids, such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), α-linolenic acid (ALA), or linoleic acid (LA), have a particular role in counteracting cardiovascular diseases. They may regulate antioxidant potential and inflammatory reactions. Little is known whether other fatty acids, such as saturated fatty acids (e.g., short-chain fatty acids (SCFA) such as butyric or caproic acid) or monounsaturated fatty acids, may be involved and whether the level of Vitamin C intake may affect these processes. The purpose of this study was to assess the impact of fatty acid intake on plasma and salivary total antioxidant capacity (TAC), and the salivary inflammation marker C-reactive protein (CRP). Eighty older adults (60–79 years old) were divided into two groups with high (n = 39) and low (n = 41) Vitamin C intake. In the group with high Vitamin C intake SCFA, ALA, LA positively correlated with the plasma TAC indices, and in the group with low Vitamin C intake, the salivary TAC was decreased in subjects with a higher SCFA intake. Salivary CRP negatively corresponded to SCFA, EPA, and DHA in the whole study group (<i>p</i> < 0.05 for all). Fatty acids and Vitamin C intake may influence antioxidant potential and salivary CRP. |
| first_indexed | 2024-03-11T09:15:25Z |
| format | Article |
| id | doaj.art-d7c999fb9d8440d09d1a08c86b71f4b1 |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-11T09:15:25Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-d7c999fb9d8440d09d1a08c86b71f4b12023-11-16T18:45:44ZengMDPI AGAntioxidants2076-39212023-01-0112226710.3390/antiox12020267The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C IntakeAnna Gawron-Skarbek0Agnieszka Guligowska1Anna Prymont-Przymińska2Dariusz Nowak3Tomasz Kostka4Department of Geriatrics, Medical University of Lodz, 90-647 Lodz, PolandDepartment of Geriatrics, Medical University of Lodz, 90-647 Lodz, PolandDepartment of Clinical Physiology, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Clinical Physiology, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Geriatrics, Medical University of Lodz, 90-647 Lodz, PolandPolyunsaturated fatty acids, such as eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), α-linolenic acid (ALA), or linoleic acid (LA), have a particular role in counteracting cardiovascular diseases. They may regulate antioxidant potential and inflammatory reactions. Little is known whether other fatty acids, such as saturated fatty acids (e.g., short-chain fatty acids (SCFA) such as butyric or caproic acid) or monounsaturated fatty acids, may be involved and whether the level of Vitamin C intake may affect these processes. The purpose of this study was to assess the impact of fatty acid intake on plasma and salivary total antioxidant capacity (TAC), and the salivary inflammation marker C-reactive protein (CRP). Eighty older adults (60–79 years old) were divided into two groups with high (n = 39) and low (n = 41) Vitamin C intake. In the group with high Vitamin C intake SCFA, ALA, LA positively correlated with the plasma TAC indices, and in the group with low Vitamin C intake, the salivary TAC was decreased in subjects with a higher SCFA intake. Salivary CRP negatively corresponded to SCFA, EPA, and DHA in the whole study group (<i>p</i> < 0.05 for all). Fatty acids and Vitamin C intake may influence antioxidant potential and salivary CRP.https://www.mdpi.com/2076-3921/12/2/267PUFA intakeVitamin C intakeshort-chain fatty acidscardiovascular healthEPADHA |
| spellingShingle | Anna Gawron-Skarbek Agnieszka Guligowska Anna Prymont-Przymińska Dariusz Nowak Tomasz Kostka The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C Intake Antioxidants PUFA intake Vitamin C intake short-chain fatty acids cardiovascular health EPA DHA |
| title | The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C Intake |
| title_full | The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C Intake |
| title_fullStr | The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C Intake |
| title_full_unstemmed | The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C Intake |
| title_short | The Anti-Inflammatory and Antioxidant Impact of Dietary Fatty Acids in Cardiovascular Protection in Older Adults May Be Related to Vitamin C Intake |
| title_sort | anti inflammatory and antioxidant impact of dietary fatty acids in cardiovascular protection in older adults may be related to vitamin c intake |
| topic | PUFA intake Vitamin C intake short-chain fatty acids cardiovascular health EPA DHA |
| url | https://www.mdpi.com/2076-3921/12/2/267 |
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