Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019
Background and purpose: Proton pump inhibitors (PPIs) are one of the main therapeutic agents for acid-related diseases. Pantoprazole, with minimal drug interaction, is one of the well-known PPIs. According to various studies, 25-75% of pantoprazole injections have no indications and cause a high bur...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2022-01-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-16871-en.html |
| _version_ | 1797893732522000384 |
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| author | Adeleh Sahebnasagh Ali Basiratian Amirhossein Zahmatkesh Majid Hajimaghsoudi Fatemeh Saghafi |
| author_facet | Adeleh Sahebnasagh Ali Basiratian Amirhossein Zahmatkesh Majid Hajimaghsoudi Fatemeh Saghafi |
| author_sort | Adeleh Sahebnasagh |
| collection | DOAJ |
| description | Background and purpose: Proton pump inhibitors (PPIs) are one of the main therapeutic agents for acid-related diseases. Pantoprazole, with minimal drug interaction, is one of the well-known PPIs. According to various studies, 25-75% of pantoprazole injections have no indications and cause a high burden on health systems. The aim of this study was to investigate the indication and rate of pantoprazole injections in Yazd Rahnemoon Hospital, Iran.
Materials and methods: This cross-sectional study was performed in 72 hospitalized patients in invasive care units, and internal and emergency wards between March and December 2019. Demographic and clinical data, risk factors, PPI indication, and doses of utilized pantoprazole were recorded. The rationality of pantoprazole prescription was confirmed by comparing the drug information from up-to-date database under the supervision of a clinical pharmacist in the hospital.
Results: In total, out of 60 patients who received IV pantoprazole, 52.8% could have received the oral form and in 69.4% there was no indication to use IV pantoprazole.
Conclusion: In this study, parenteral form of pantoprazole was not indicated in majority of the patients. Guidelines should be approved to prevent irrational administration of parental PPIs in hospitals. |
| first_indexed | 2024-04-10T06:57:37Z |
| format | Article |
| id | doaj.art-d7cbef60c64d4c6788bbe9e98a7d2c3c |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T06:57:37Z |
| publishDate | 2022-01-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-d7cbef60c64d4c6788bbe9e98a7d2c3c2023-02-28T06:41:33ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792022-01-0131204151156Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019Adeleh Sahebnasagh0Ali Basiratian1Amirhossein Zahmatkesh2Majid Hajimaghsoudi3Fatemeh Saghafi4 Assistant Professor, Department of Internal Medicine, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran Doctor of Pharmacy, Student Research Committee, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Doctor of Pharmacy, Student Research Committee, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Associate Professor, Department of Emergency Medicine, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Assistant Professor, Department of Clinical Pharmacy, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Background and purpose: Proton pump inhibitors (PPIs) are one of the main therapeutic agents for acid-related diseases. Pantoprazole, with minimal drug interaction, is one of the well-known PPIs. According to various studies, 25-75% of pantoprazole injections have no indications and cause a high burden on health systems. The aim of this study was to investigate the indication and rate of pantoprazole injections in Yazd Rahnemoon Hospital, Iran. Materials and methods: This cross-sectional study was performed in 72 hospitalized patients in invasive care units, and internal and emergency wards between March and December 2019. Demographic and clinical data, risk factors, PPI indication, and doses of utilized pantoprazole were recorded. The rationality of pantoprazole prescription was confirmed by comparing the drug information from up-to-date database under the supervision of a clinical pharmacist in the hospital. Results: In total, out of 60 patients who received IV pantoprazole, 52.8% could have received the oral form and in 69.4% there was no indication to use IV pantoprazole. Conclusion: In this study, parenteral form of pantoprazole was not indicated in majority of the patients. Guidelines should be approved to prevent irrational administration of parental PPIs in hospitals.http://jmums.mazums.ac.ir/article-1-16871-en.htmlpantoprazoleproton pump inhibitordrug utilization evaluationrational administration |
| spellingShingle | Adeleh Sahebnasagh Ali Basiratian Amirhossein Zahmatkesh Majid Hajimaghsoudi Fatemeh Saghafi Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019 Journal of Mazandaran University of Medical Sciences pantoprazole proton pump inhibitor drug utilization evaluation rational administration |
| title | Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019 |
| title_full | Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019 |
| title_fullStr | Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019 |
| title_full_unstemmed | Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019 |
| title_short | Investigating the Use of Pantoprazole in Yazd Shahid Rahnemoon Hospital, 2019 |
| title_sort | investigating the use of pantoprazole in yazd shahid rahnemoon hospital 2019 |
| topic | pantoprazole proton pump inhibitor drug utilization evaluation rational administration |
| url | http://jmums.mazums.ac.ir/article-1-16871-en.html |
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