Research progress on P2X7 receptor in cancer pain

Research progress on P2X7 receptor in cancer pain

The activation of the P2X7 receptor as an ATP-gated ion channel, triggers the release of pro-inflammatory cytokines in tumor carring individuals and stimulate excitation of injury-causing neurons, thereby exacerbating the transmission of pain. In preclinical cancer pain models, it has the potential...

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Bibliographic Details
Main Author:	ZHANG Zhongwen, ZHAO Rui, ZHANG Haolong, YANG Yuting, BAI Jinxia, ZHANG Haoling WANG Wei
Format:	Article
Language:	zho
Published:	Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2024-03-01
Series:	Jichu yixue yu linchuang
Subjects:	p2x7 receptor\|cancer pain\|glial cell\|p2x7 antagonist
Online Access:	http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2024-44-3-389.pdf

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