The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

Genetic studies in T-cell acute lymphoblastic leukemia have uncovered a remarkable complexity of oncogenic and loss-of-function mutations. Amongst this plethora of genetic changes, NOTCH1 activating mutations stand out as the most frequently occurring genetic defect, identified in more than 50% of T...

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Bibliographic Details
Main Authors: Kaat Durinck, Annelynn Wallaert, Inge Van de Walle, Wouter Van Loocke, Pieter-Jan Volders, Suzanne Vanhauwaert, Ellen Geerdens, Yves Benoit, Nadine Van Roy, Bruce Poppe, Jean Soulier, Jan Cools, Pieter Mestdagh, Jo Vandesompele, Pieter Rondou, Pieter Van Vlierberghe, Tom Taghon, Frank Speleman
Format: Article
Language:English
Published: Ferrata Storti Foundation 2014-12-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/7221

Internet

https://haematologica.org/article/view/7221

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