The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal Cord
This study was designed to evaluate the analgesic effect of bee venom (BV) Acupuncture into different treatment points, Chok-samni (ST36) and blank loci of the gluteal muscle and back. We investigated neuronal activity in the spinal cord using the Fos immunohistochemical technique according to the p...
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| Format: | Article |
| Language: | English |
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Korean Pharmacopuncture Institute
2000-07-01
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| Series: | Journal of Pharmacopuncture |
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| Online Access: | http://dx.doi.org/10.3831/KPI.2000.3.1.141 |
| _version_ | 1818391318798270464 |
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| author | Yim Yun-Kyoung Kang Sung-Keel Choi Do-Young |
| author_facet | Yim Yun-Kyoung Kang Sung-Keel Choi Do-Young |
| author_sort | Yim Yun-Kyoung |
| collection | DOAJ |
| description | This study was designed to evaluate the analgesic effect of bee venom (BV) Acupuncture into different treatment points, Chok-samni (ST36) and blank loci of the gluteal muscle and back. We investigated neuronal activity in the spinal cord using the Fos immunohistochemical technique according to the pretreatment with different concentrations of BV, thirty minutes before the formalin injection. The results were summarized as follows:
1. The number of Fos-like immunoreactive (Fos-LI) neurons in L2 segment of the saline-formalin treated group was significantly increased in NECK and VENT of the spinal cord as compared with that of the room control group. However, there was no significant change in the number of the Fos-LI neurons in L2 segment of the BV-formalin treated group as compared with that of the room control group.
2. The number of Fos-LI neurons in L3-5 segment of the saline-formalin group was significantly increased in all the regions of the spinal cord as compared with that of the room control group. However, the Fos-LI neurons in L3-5 segment of the BV-formalin treated group was dramatically decreased in all the regions of the spinal cord as compared with that of the saline-formalin group. Therefore, these results indicated that the BV acupuncture suppressed the nociceptive neuronal activities in L3-5 of the spinal cord induced by formalin injection.
3. There was a strong positive correlation between the formalin-induced pain behavior and the number of the Fos-LI neurons in L3-5 segment. |
| first_indexed | 2024-12-14T05:11:37Z |
| format | Article |
| id | doaj.art-d7d0586a330c49b68fb071c28a80409e |
| institution | Directory Open Access Journal |
| issn | 2093-6966 2234-6856 |
| language | English |
| last_indexed | 2024-12-14T05:11:37Z |
| publishDate | 2000-07-01 |
| publisher | Korean Pharmacopuncture Institute |
| record_format | Article |
| series | Journal of Pharmacopuncture |
| spelling | doaj.art-d7d0586a330c49b68fb071c28a80409e2022-12-21T23:15:57ZengKorean Pharmacopuncture InstituteJournal of Pharmacopuncture2093-69662234-68562000-07-013114115510.3831/KPI.2000.3.1.141The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal CordYim Yun-Kyoung 0Kang Sung-Keel 1Choi Do-Young 2Dept. of Acupuncture & Moxibustion Oriental Medical College, KyungHee UniversityDept. of Acupuncture & Moxibustion Oriental Medical College, KyungHee UniversityDept. of Acupuncture & Moxibustion Oriental Medical College, KyungHee UniversityThis study was designed to evaluate the analgesic effect of bee venom (BV) Acupuncture into different treatment points, Chok-samni (ST36) and blank loci of the gluteal muscle and back. We investigated neuronal activity in the spinal cord using the Fos immunohistochemical technique according to the pretreatment with different concentrations of BV, thirty minutes before the formalin injection. The results were summarized as follows: 1. The number of Fos-like immunoreactive (Fos-LI) neurons in L2 segment of the saline-formalin treated group was significantly increased in NECK and VENT of the spinal cord as compared with that of the room control group. However, there was no significant change in the number of the Fos-LI neurons in L2 segment of the BV-formalin treated group as compared with that of the room control group. 2. The number of Fos-LI neurons in L3-5 segment of the saline-formalin group was significantly increased in all the regions of the spinal cord as compared with that of the room control group. However, the Fos-LI neurons in L3-5 segment of the BV-formalin treated group was dramatically decreased in all the regions of the spinal cord as compared with that of the saline-formalin group. Therefore, these results indicated that the BV acupuncture suppressed the nociceptive neuronal activities in L3-5 of the spinal cord induced by formalin injection. 3. There was a strong positive correlation between the formalin-induced pain behavior and the number of the Fos-LI neurons in L3-5 segment.http://dx.doi.org/10.3831/KPI.2000.3.1.141bee venom (BV) acupunctureChok-samni (ST36)Fos-like immunoreactive (Fos-LI) neuron |
| spellingShingle | Yim Yun-Kyoung Kang Sung-Keel Choi Do-Young The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal Cord Journal of Pharmacopuncture bee venom (BV) acupuncture Chok-samni (ST36) Fos-like immunoreactive (Fos-LI) neuron |
| title | The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal Cord |
| title_full | The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal Cord |
| title_fullStr | The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal Cord |
| title_full_unstemmed | The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal Cord |
| title_short | The Effect of Bee Venom Acupuncture into Chok-samni (ST36) on Neuronal Activity in the Spinal Cord |
| title_sort | effect of bee venom acupuncture into chok samni st36 on neuronal activity in the spinal cord |
| topic | bee venom (BV) acupuncture Chok-samni (ST36) Fos-like immunoreactive (Fos-LI) neuron |
| url | http://dx.doi.org/10.3831/KPI.2000.3.1.141 |
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