Relationship between Serum Caffeine and Preeclampsia in Pregnant Women
Background: Preeclampsia is a vascular disease that happens during pregnancy. It is created by vasospasm and vascular endothelium activity and is one of the most important complications of pregnancy. Blood pressure disorders in pregnancy are one of the three major reasons of mothers’ mortality. The...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2011-11-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/993 |
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| author | Ziba Doozandeh Tahereh Keshavarz Zohreh Tavana Zinab Moshfegh Mehrab Sayadi |
| author_facet | Ziba Doozandeh Tahereh Keshavarz Zohreh Tavana Zinab Moshfegh Mehrab Sayadi |
| author_sort | Ziba Doozandeh |
| collection | DOAJ |
| description | Background: Preeclampsia is a vascular disease that happens during pregnancy. It is created by vasospasm and vascular endothelium activity and is one of the most important complications of pregnancy. Blood pressure disorders in pregnancy are one of the three major reasons of mothers’ mortality. The aim of this study was to determine the relation between serum caffeine and preeclampsia in pregnancy.
Methods: This study was a case-control study. 44 pregnant women in Shiraz, aged 18-35 years, were enrolled in the study. Based on the criteria of entering, 22 women with preeclampsia and 22 women with normal blood pressure have been selected by systematic random sampling from women who were reffered to 2 hospitals in Shiraz. Initially, demographic data and daily caffeine intake was gathered. Then serum caffeine level was measured for all of the subjects. The data was analyzed by Student t-test and multivariate logistic regression.
Findings: The mean amount of serum caffeine was 0.309 ± 0.292 and 0.468 ± 0.314 in case group and control group, respectively (P = 0.094). Logestic regression analysis did not show a significant correlation between serum caffeine levels and preeclampsia (OR= 0.565, 95% CI: 0.013-25.42). The correlation between maternal age (OR = 1.52, 95% CI: 1.08- 2.15) and gestational age (OR = 1.43, 95% CI: 1.09-1.87) with preeclampsia were significant.
Conclusion: There is no significance relationship between preeclampsia and the caffeine level of the serum based on our findings. Therefore, restricting the caffeine consumption in pregnant women does not seem rational. |
| first_indexed | 2024-03-12T19:35:54Z |
| format | Article |
| id | doaj.art-d7d4a57384e9484499364a1a891259fa |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T19:35:54Z |
| publishDate | 2011-11-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-d7d4a57384e9484499364a1a891259fa2023-08-02T04:11:53ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-11-012915614541461764Relationship between Serum Caffeine and Preeclampsia in Pregnant WomenZiba Doozandeh0Tahereh Keshavarz1Zohreh Tavana2Zinab Moshfegh3Mehrab Sayadi4MSc, Department of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, IranLecturer, Department of Midwifery, Fatemeh (PBUH) School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, IranAssistant Professor, Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranLecturer, Department of Midwifery, Fatemeh (PBUH) School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, IranMSc of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IranBackground: Preeclampsia is a vascular disease that happens during pregnancy. It is created by vasospasm and vascular endothelium activity and is one of the most important complications of pregnancy. Blood pressure disorders in pregnancy are one of the three major reasons of mothers’ mortality. The aim of this study was to determine the relation between serum caffeine and preeclampsia in pregnancy. Methods: This study was a case-control study. 44 pregnant women in Shiraz, aged 18-35 years, were enrolled in the study. Based on the criteria of entering, 22 women with preeclampsia and 22 women with normal blood pressure have been selected by systematic random sampling from women who were reffered to 2 hospitals in Shiraz. Initially, demographic data and daily caffeine intake was gathered. Then serum caffeine level was measured for all of the subjects. The data was analyzed by Student t-test and multivariate logistic regression. Findings: The mean amount of serum caffeine was 0.309 ± 0.292 and 0.468 ± 0.314 in case group and control group, respectively (P = 0.094). Logestic regression analysis did not show a significant correlation between serum caffeine levels and preeclampsia (OR= 0.565, 95% CI: 0.013-25.42). The correlation between maternal age (OR = 1.52, 95% CI: 1.08- 2.15) and gestational age (OR = 1.43, 95% CI: 1.09-1.87) with preeclampsia were significant. Conclusion: There is no significance relationship between preeclampsia and the caffeine level of the serum based on our findings. Therefore, restricting the caffeine consumption in pregnant women does not seem rational.http://jims.mui.ac.ir/index.php/jims/article/view/993CaffeinePreeclampsiaPregnancy |
| spellingShingle | Ziba Doozandeh Tahereh Keshavarz Zohreh Tavana Zinab Moshfegh Mehrab Sayadi Relationship between Serum Caffeine and Preeclampsia in Pregnant Women مجله دانشکده پزشکی اصفهان Caffeine Preeclampsia Pregnancy |
| title | Relationship between Serum Caffeine and Preeclampsia in Pregnant Women |
| title_full | Relationship between Serum Caffeine and Preeclampsia in Pregnant Women |
| title_fullStr | Relationship between Serum Caffeine and Preeclampsia in Pregnant Women |
| title_full_unstemmed | Relationship between Serum Caffeine and Preeclampsia in Pregnant Women |
| title_short | Relationship between Serum Caffeine and Preeclampsia in Pregnant Women |
| title_sort | relationship between serum caffeine and preeclampsia in pregnant women |
| topic | Caffeine Preeclampsia Pregnancy |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/993 |
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