Pharmacokinetic criteria of ketoprofen and its cyclooxygenase-2 inhibition in mice: influence of xylazine administration

Pharmacokinetic criteria of ketoprofen and its cyclooxygenase-2 inhibition in mice: influence of xylazine administration

The objective of this study was to examine the effect of ketoprofen with or without combination with xylazine on the level of cyclooxygenase-2 in mice. The intraperitoneal (i.p.) dose of ketoprofen and xylazine that caused an analgesic response in half of the mouse population was 1.26 mg/kg and 6.63...

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Bibliographic Details
Main Authors: Khalil Abdullah Khalil, Yaareb Jaafer Mousa, Muna Hazim Alzubaidy
Format: Article
Language:English
Published: Ss.Cyril and Methodius University, Skopje 2023-03-01
Series:Macedonian Veterinary Review
Subjects:
cyclooxygenase-2
ketoprofen
mice
pharmacokinetics
xylazine
Online Access:https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2022_0031

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