A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria
Background: Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first diagnosis in pregnancy. GDM has numerous potential complications and it is important to estimate its burden and risk factors. The objective of the meta-analysis was to determine the pooled preval...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2021;volume=25;issue=3;spage=182;epage=190;aulast=Azeez |
| _version_ | 1818823784793112576 |
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| author | Taoreed Adegoke Azeez Tamunosaki Abo-Briggs Ayodeji Sylvester Adeyanju |
| author_facet | Taoreed Adegoke Azeez Tamunosaki Abo-Briggs Ayodeji Sylvester Adeyanju |
| author_sort | Taoreed Adegoke Azeez |
| collection | DOAJ |
| description | Background: Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first diagnosis in pregnancy. GDM has numerous potential complications and it is important to estimate its burden and risk factors. The objective of the meta-analysis was to determine the pooled prevalence of GDM in Nigeria and identify its determinants. Methods: The study design was a meta-analysis; therefore the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Electronic databases (African Journal Online, PubMed, SCOPUS, and Google Scholar) and the gray literature were systematically searched. Statistical analysis was done with MetaXL using the random effect model. Heterogeneity was determined using the I2 statistic and the publication bias was checked with the Doi plot. Results: The total sample size was 46 210. The prevalence of GDM in Nigeria was 0.5 – 38% and the pooled prevalence was 11.0% (95% CI 8-13). The I2 statistic was 99%. The Doi plot suggested some degree of bias. The most frequently reported determinants of GDM were previous macrosomic babies, maternal obesity, family history of diabetes, previous miscarriage, and advanced maternal age. Conclusion: The prevalence of GDM in Nigeria is high and efforts should be geared at modifying its risk factors so as to reduce its prevalence and prevent the associated complications. |
| first_indexed | 2024-12-18T23:45:29Z |
| format | Article |
| id | doaj.art-d7dff48d8b784a418fb56488e98e534d |
| institution | Directory Open Access Journal |
| issn | 2230-8210 |
| language | English |
| last_indexed | 2024-12-18T23:45:29Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-d7dff48d8b784a418fb56488e98e534d2022-12-21T20:47:14ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102021-01-0125318219010.4103/ijem.ijem_301_21A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in NigeriaTaoreed Adegoke AzeezTamunosaki Abo-BriggsAyodeji Sylvester AdeyanjuBackground: Gestational diabetes mellitus (GDM) is any degree of glucose intolerance with onset or first diagnosis in pregnancy. GDM has numerous potential complications and it is important to estimate its burden and risk factors. The objective of the meta-analysis was to determine the pooled prevalence of GDM in Nigeria and identify its determinants. Methods: The study design was a meta-analysis; therefore the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. Electronic databases (African Journal Online, PubMed, SCOPUS, and Google Scholar) and the gray literature were systematically searched. Statistical analysis was done with MetaXL using the random effect model. Heterogeneity was determined using the I2 statistic and the publication bias was checked with the Doi plot. Results: The total sample size was 46 210. The prevalence of GDM in Nigeria was 0.5 – 38% and the pooled prevalence was 11.0% (95% CI 8-13). The I2 statistic was 99%. The Doi plot suggested some degree of bias. The most frequently reported determinants of GDM were previous macrosomic babies, maternal obesity, family history of diabetes, previous miscarriage, and advanced maternal age. Conclusion: The prevalence of GDM in Nigeria is high and efforts should be geared at modifying its risk factors so as to reduce its prevalence and prevent the associated complications.http://www.ijem.in/article.asp?issn=2230-8210;year=2021;volume=25;issue=3;spage=182;epage=190;aulast=Azeezgestational diabetesmeta-analysisnigeriaprevalencerisk factors |
| spellingShingle | Taoreed Adegoke Azeez Tamunosaki Abo-Briggs Ayodeji Sylvester Adeyanju A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria Indian Journal of Endocrinology and Metabolism gestational diabetes meta-analysis nigeria prevalence risk factors |
| title | A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria |
| title_full | A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria |
| title_fullStr | A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria |
| title_full_unstemmed | A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria |
| title_short | A systematic review and meta-analysis of the prevalence and determinants of gestational diabetes mellitus in Nigeria |
| title_sort | systematic review and meta analysis of the prevalence and determinants of gestational diabetes mellitus in nigeria |
| topic | gestational diabetes meta-analysis nigeria prevalence risk factors |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2021;volume=25;issue=3;spage=182;epage=190;aulast=Azeez |
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