Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma
Bone metastasis occurs frequently in patients with nasopharyngeal carcinoma (NPC). Although fluorine-18 fluorodeoxyglucose positron emission tomography with computed tomography (PET/CT) has been proven to be more sensitive at detecting bone metastases than Technetium-99m methylene diphosphonate skel...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2022-08-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605221116765 |
| _version_ | 1828434971202682880 |
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| author | Wei-Jheng Yen Chih-Ting Liu Ya-Min Chi Chin-Chuan Chang |
| author_facet | Wei-Jheng Yen Chih-Ting Liu Ya-Min Chi Chin-Chuan Chang |
| author_sort | Wei-Jheng Yen |
| collection | DOAJ |
| description | Bone metastasis occurs frequently in patients with nasopharyngeal carcinoma (NPC). Although fluorine-18 fluorodeoxyglucose positron emission tomography with computed tomography (PET/CT) has been proven to be more sensitive at detecting bone metastases than Technetium-99m methylene diphosphonate skeletal scintigraphy in pretreatment patients with NPC in most clinical settings, there have been metastatic lesions that were positive on skeletal scintigraphy but negative on PET/CT scans. Herein, we report the case of a patient with stage IV NPC that manifested as multiple metabolically abnormal lesions on pretreatment skeletal scintigraphy and were considered malignant although they were negative on PET/CT examination. Follow-up evaluations with both skeletal scintigraphy and PET/CT scans as post-therapeutic imaging are also presented. |
| first_indexed | 2024-12-10T18:59:30Z |
| format | Article |
| id | doaj.art-d7e3e59306b0465c85076bdeada922f6 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-12-10T18:59:30Z |
| publishDate | 2022-08-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-d7e3e59306b0465c85076bdeada922f62022-12-22T01:37:03ZengSAGE PublishingJournal of International Medical Research1473-23002022-08-015010.1177/03000605221116765Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinomaWei-Jheng YenChih-Ting LiuYa-Min ChiChin-Chuan ChangBone metastasis occurs frequently in patients with nasopharyngeal carcinoma (NPC). Although fluorine-18 fluorodeoxyglucose positron emission tomography with computed tomography (PET/CT) has been proven to be more sensitive at detecting bone metastases than Technetium-99m methylene diphosphonate skeletal scintigraphy in pretreatment patients with NPC in most clinical settings, there have been metastatic lesions that were positive on skeletal scintigraphy but negative on PET/CT scans. Herein, we report the case of a patient with stage IV NPC that manifested as multiple metabolically abnormal lesions on pretreatment skeletal scintigraphy and were considered malignant although they were negative on PET/CT examination. Follow-up evaluations with both skeletal scintigraphy and PET/CT scans as post-therapeutic imaging are also presented.https://doi.org/10.1177/03000605221116765 |
| spellingShingle | Wei-Jheng Yen Chih-Ting Liu Ya-Min Chi Chin-Chuan Chang Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma Journal of International Medical Research |
| title | Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma |
| title_full | Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma |
| title_fullStr | Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma |
| title_full_unstemmed | Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma |
| title_short | Skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma |
| title_sort | skeletal scintigraphy as an important complement for detecting bone metastasis from nasopharyngeal carcinoma |
| url | https://doi.org/10.1177/03000605221116765 |
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