Abatacept is effective in Chinese patients with LRBA and CTLA4 deficiency

Abatacept is effective in Chinese patients with LRBA and CTLA4 deficiency

CTLA4 deficiency and LRBA deficiency are a group disorders of immune dysregulation that affect CTLA4 pathway. The patients mainly present with autoimmunity, antibody deficiency and recurrent infections. Here we reported three Chinese patients with LRBA and CTLA4 mutations. They all presented with ch...

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Bibliographic Details
Main Authors: Lu Yang, Xiuhong Xue, Xuemei Chen, Junfeng Wu, Xi Yang, Li Xu, Xuemei Tang, Mo Wang, Huawei Mao, Xiaodong Zhao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-09-01
Series:Genes and Diseases
Subjects:
LRBA deficiency
CTLA4 deficiency
Target therapy
Abatacept
Efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220300350

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