Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes
Aim. To assess visceral adiposity index (VAI) in patients with coronary artery disease (CAD) and overweight or obesity, as well as to determine its relationship with lipid and carbohydrate metabolism parameters and inflammatory markers, depending on the presence of carbohydrate metabolism disorders...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2020-07-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/2311 |
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| author | A. A. Khorlampenko V. N. Karetnikova A. M. Kochergina Yu. S. Ignatova E. V. Belik O. V. Gruzdeva N. K. Brel A. N. Kokov O. L. Barbarash |
| author_facet | A. A. Khorlampenko V. N. Karetnikova A. M. Kochergina Yu. S. Ignatova E. V. Belik O. V. Gruzdeva N. K. Brel A. N. Kokov O. L. Barbarash |
| author_sort | A. A. Khorlampenko |
| collection | DOAJ |
| description | Aim. To assess visceral adiposity index (VAI) in patients with coronary artery disease (CAD) and overweight or obesity, as well as to determine its relationship with lipid and carbohydrate metabolism parameters and inflammatory markers, depending on the presence of carbohydrate metabolism disorders (CMD).Material and methods. The study included 95 patients with CAD and overweight (body mass index (BMI) >25 kg/m2) or obesity (BMI >30 kg/m2), of which 59 patients had type 2 diabetes (T2D) and 36 were without CMD. All patients were assessed for obesity; VAI was calculated. Following laboratory parameters were evaluated: glucose, glycated hemoglobin, C-reactive protein, adiponectin, lipid panel. In patients without history of CMD, an oral glucose tolerance test was performed.Results. Compared with patients without CMD, subjects with T2D had significantly higher values of BMI, waist circumference, as well as the body fat percentage, area and volume of visceral adipose tissue estimated by computed tomography. Analysis of lipid profile, C-reactive protein and adiponectin levels did not reveal significant differences between the groups. VAI also did not significantly differ in both groups. VAI had the most correlations with clinical and metabolic parameters in both patients with T2D and without CMD. Other methods for assessing obesity were less correlated with laboratory parameters in both groups. Only VAI significantly correlated with adiponectin in both groups.Conclusion. The obtained correlations between VAI and clinical and metabolic parameters confirm the practicability of using it to determine adipose tissue dysfunction in patients with/without CMD. The effect of increased VAI on the cardiovascular risk in high-risk patients requires further study. |
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| format | Article |
| id | doaj.art-d7e5dd1a25e5421ca1f8a04355e1384a |
| institution | Directory Open Access Journal |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| last_indexed | 2025-03-19T22:36:56Z |
| publishDate | 2020-07-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-d7e5dd1a25e5421ca1f8a04355e1384a2024-10-17T12:21:39Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252020-07-0119310.15829/1728-8800-2020-23112095Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetesA. A. Khorlampenko0V. N. Karetnikova1A. M. Kochergina2Yu. S. Ignatova3E. V. Belik4O. V. Gruzdeva5N. K. Brel6A. N. Kokov7O. L. Barbarash8Kemerovo State Medical UniversityKemerovo State Medical University; Research Institute for Complex Issues of Cardiovascular DiseasesKemerovo State Medical University; Research Institute for Complex Issues of Cardiovascular DiseasesKemerovo State Medical UniversityResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesKemerovo State Medical University; Research Institute for Complex Issues of Cardiovascular DiseasesAim. To assess visceral adiposity index (VAI) in patients with coronary artery disease (CAD) and overweight or obesity, as well as to determine its relationship with lipid and carbohydrate metabolism parameters and inflammatory markers, depending on the presence of carbohydrate metabolism disorders (CMD).Material and methods. The study included 95 patients with CAD and overweight (body mass index (BMI) >25 kg/m2) or obesity (BMI >30 kg/m2), of which 59 patients had type 2 diabetes (T2D) and 36 were without CMD. All patients were assessed for obesity; VAI was calculated. Following laboratory parameters were evaluated: glucose, glycated hemoglobin, C-reactive protein, adiponectin, lipid panel. In patients without history of CMD, an oral glucose tolerance test was performed.Results. Compared with patients without CMD, subjects with T2D had significantly higher values of BMI, waist circumference, as well as the body fat percentage, area and volume of visceral adipose tissue estimated by computed tomography. Analysis of lipid profile, C-reactive protein and adiponectin levels did not reveal significant differences between the groups. VAI also did not significantly differ in both groups. VAI had the most correlations with clinical and metabolic parameters in both patients with T2D and without CMD. Other methods for assessing obesity were less correlated with laboratory parameters in both groups. Only VAI significantly correlated with adiponectin in both groups.Conclusion. The obtained correlations between VAI and clinical and metabolic parameters confirm the practicability of using it to determine adipose tissue dysfunction in patients with/without CMD. The effect of increased VAI on the cardiovascular risk in high-risk patients requires further study.https://cardiovascular.elpub.ru/jour/article/view/2311visceral obesity indexdiabetesadiponectincoronary artery disease |
| spellingShingle | A. A. Khorlampenko V. N. Karetnikova A. M. Kochergina Yu. S. Ignatova E. V. Belik O. V. Gruzdeva N. K. Brel A. N. Kokov O. L. Barbarash Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes Кардиоваскулярная терапия и профилактика visceral obesity index diabetes adiponectin coronary artery disease |
| title | Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes |
| title_full | Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes |
| title_fullStr | Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes |
| title_full_unstemmed | Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes |
| title_short | Visceral adiposity index in patients with coronary artery disease, obesity and type 2 diabetes |
| title_sort | visceral adiposity index in patients with coronary artery disease obesity and type 2 diabetes |
| topic | visceral obesity index diabetes adiponectin coronary artery disease |
| url | https://cardiovascular.elpub.ru/jour/article/view/2311 |
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