Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression

Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression

Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal metastatic disease associated with robust activation of the coagulation and fibrinolytic systems. However, the potential contribution of the primary fibrinolytic protease plasminogen to PDAC disease progression has remained largely undefined....

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Bibliographic Details
Main Authors: Nayela N. Chowdhury, Yi Yang, Ananya Dutta, Michelle Luo, Zimu Wei, Sara R. Abrahams, Alexey S. Revenko, Fenil Shah, Lindsey A. Miles, Robert J. Parmer, Bas deLaat, Alisa S. Wolberg, James P. Luyendyk, Melissa L. Fishel, Matthew J. Flick
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Molecular Oncology
Subjects:
metastasis
mouse model
PDAC
plasminogen
Online Access:https://doi.org/10.1002/1878-0261.13552

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