Voriconazole Cyclodextrin Based Polymeric Nanobeads for Enhanced Solubility and Activity: In Vitro/In Vivo and Molecular Simulation Approach

Voriconazole Cyclodextrin Based Polymeric Nanobeads for Enhanced Solubility and Activity: In Vitro/In Vivo and Molecular Simulation Approach

Hydroxypropyl β-cyclodextrin (HPβCD) based polymeric nanobeads containing voriconazole (VRC) were fabricated by free radical polymerization using <i>N, N</i>′-methylene bisacrylamide (MBA) as a cross-linker, 2-acrylamide-2-methylpropane sulfonic acid (AMPS) as monomer and ammonium persul...

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Bibliographic Details
Main Authors: Mudassir Farooq, Faisal Usman, Mahrukh Naseem, Hanan Y. Aati, Hassan Ahmad, Sirikhwan Manee, Ruqaiya Khalil, Kashif ur Rehman Khan, Muhammad Imran Qureshi, Muhammad Umair
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
voriconazole
hydroxy propyl β cyclodextrin
fungal infection
nanobeads
free radical polymerization
Online Access:https://www.mdpi.com/1999-4923/15/2/389

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https://www.mdpi.com/1999-4923/15/2/389

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