Self-organization of songbird neural sequences during social isolation
Behaviors emerge via a combination of experience and innate predispositions. As the brain matures, it undergoes major changes in cellular, network, and functional properties that can be due to sensory experience as well as developmental processes. In normal birdsong learning, neural sequences emerge...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2023-05-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/77262 |
| _version_ | 1797816556473810944 |
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| author | Emily L Mackevicius Shijie Gu Natalia I Denisenko Michale S Fee |
| author_facet | Emily L Mackevicius Shijie Gu Natalia I Denisenko Michale S Fee |
| author_sort | Emily L Mackevicius |
| collection | DOAJ |
| description | Behaviors emerge via a combination of experience and innate predispositions. As the brain matures, it undergoes major changes in cellular, network, and functional properties that can be due to sensory experience as well as developmental processes. In normal birdsong learning, neural sequences emerge to control song syllables learned from a tutor. Here, we disambiguate the role of tutor experience and development in neural sequence formation by delaying exposure to a tutor. Using functional calcium imaging, we observe neural sequences in the absence of tutoring, demonstrating that tutor experience is not necessary for the formation of sequences. However, after exposure to a tutor, pre-existing sequences can become tightly associated with new song syllables. Since we delayed tutoring, only half our birds learned new syllables following tutor exposure. The birds that failed to learn were the birds in which pre-tutoring neural sequences were most ‘crystallized,’ that is, already tightly associated with their (untutored) song. |
| first_indexed | 2024-03-13T08:39:28Z |
| format | Article |
| id | doaj.art-d7ed953ac18e4c85bf77faecb07558c6 |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-03-13T08:39:28Z |
| publishDate | 2023-05-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-d7ed953ac18e4c85bf77faecb07558c62023-05-30T15:45:09ZengeLife Sciences Publications LtdeLife2050-084X2023-05-011210.7554/eLife.77262Self-organization of songbird neural sequences during social isolationEmily L Mackevicius0https://orcid.org/0000-0001-6593-4398Shijie Gu1https://orcid.org/0000-0001-6257-5756Natalia I Denisenko2Michale S Fee3https://orcid.org/0000-0001-7539-1745McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, MIT, Cambridge, United StatesMcGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, MIT, Cambridge, United StatesMcGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, MIT, Cambridge, United StatesMcGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, MIT, Cambridge, United StatesBehaviors emerge via a combination of experience and innate predispositions. As the brain matures, it undergoes major changes in cellular, network, and functional properties that can be due to sensory experience as well as developmental processes. In normal birdsong learning, neural sequences emerge to control song syllables learned from a tutor. Here, we disambiguate the role of tutor experience and development in neural sequence formation by delaying exposure to a tutor. Using functional calcium imaging, we observe neural sequences in the absence of tutoring, demonstrating that tutor experience is not necessary for the formation of sequences. However, after exposure to a tutor, pre-existing sequences can become tightly associated with new song syllables. Since we delayed tutoring, only half our birds learned new syllables following tutor exposure. The birds that failed to learn were the birds in which pre-tutoring neural sequences were most ‘crystallized,’ that is, already tightly associated with their (untutored) song.https://elifesciences.org/articles/77262zebra finchneural sequencescalcium imagingvocal learning |
| spellingShingle | Emily L Mackevicius Shijie Gu Natalia I Denisenko Michale S Fee Self-organization of songbird neural sequences during social isolation eLife zebra finch neural sequences calcium imaging vocal learning |
| title | Self-organization of songbird neural sequences during social isolation |
| title_full | Self-organization of songbird neural sequences during social isolation |
| title_fullStr | Self-organization of songbird neural sequences during social isolation |
| title_full_unstemmed | Self-organization of songbird neural sequences during social isolation |
| title_short | Self-organization of songbird neural sequences during social isolation |
| title_sort | self organization of songbird neural sequences during social isolation |
| topic | zebra finch neural sequences calcium imaging vocal learning |
| url | https://elifesciences.org/articles/77262 |
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