Phase transition and remodeling complex assembly are important for SS18-SSX oncogenic activity in synovial sarcomas
Oncoprotein SS18-SSX is a hallmark of synovial sarcoma. Here the authors report phase separation of SS18-SSX and the binding of SS18-SSX to chromatin remodeling complex are important for the transformation activity of the oncoprotein SS18-SSX.
Bibliographic Details
| Main Authors: |
Yanli Cheng,
Zhongtian Shen,
Yaqi Gao,
Feilong Chen,
Huisha Xu,
Qinling Mo,
Xinlei Chu,
Chang-liang Peng,
Takese T. McKenzie,
Bridgitte E. Palacios,
Jian Hu,
Hao Zhou,
Jiafu Long |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-05-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-30447-9
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