Mitochondrial complex I subunit MT-ND1 mutations affect disease progression

Mitochondrial complex I subunit MT-ND1 mutations affect disease progression

Mitochondrial respiratory chain complex I is an important component of the oxidative respiratory chain, with the mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 (MT-ND1) being one of the core subunits. MT-ND1 plays a role in the assembly of complex I and its enzymatic function....

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Bibliographic Details
Main Authors: Xi Lin, Yanhong Zhou, Lei Xue
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Mitochondrial complex I
MT-ND1
Mutation
Pathological mutation
LHON
Type 2 diabetes
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024048394

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