Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains
Abstract The analysis of microbial genomes from human archaeological samples offers a historic snapshot of ancient pathogens and provides insights into the origins of modern infectious diseases. Here, we analyze metagenomic datasets from 38 human archaeological samples and identify bacterial genomic...
Main Authors: | Harold P. Hodgins, Pengsheng Chen, Briallen Lobb, Xin Wei, Benjamin J. M. Tremblay, Michael J. Mansfield, Victoria C. Y. Lee, Pyung-Gang Lee, Jeffrey Coffin, Ana T. Duggan, Alexis E. Dolphin, Gabriel Renaud, Min Dong, Andrew C. Doxey |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-41174-0 |
Similar Items
-
Exploring the Evolution of Virulence Factors through Bioinformatic Data Mining
by: Andrew C. Doxey, et al.
Published: (2019-06-01) -
Insights into the evolutionary origins of clostridial neurotoxins from analysis of the <it>Clostridium botulinum </it>strain A neurotoxin gene cluster
by: Meiering Elizabeth M, et al.
Published: (2008-11-01) -
Facial neuromuscular junctions and brainstem nuclei are the target of tetanus neurotoxin in cephalic tetanus
by: Federico Fabris, et al.
Published: (2023-06-01) -
PathFams: statistical detection of pathogen-associated protein domains
by: Briallen Lobb, et al.
Published: (2021-09-01) -
Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin
by: Giulia Zanetti, et al.
Published: (2021-11-01)