The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-Analysis
Hantong Hu,1,2,* Zengtu Li,3,* Yingying Cheng,1,2,* Hong Gao1,2 1Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou City, People’s Republic of China; 2Department of Neurobiology and Acupuncture Research, t...
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| Format: | Article |
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Dove Medical Press
2022-07-01
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| Series: | Journal of Pain Research |
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| Online Access: | https://www.dovepress.com/the-efficacy-and-safety-of-acupuncture-for-depression-related-insomnia-peer-reviewed-fulltext-article-JPR |
| _version_ | 1828764052363411456 |
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| author | Hu H Li Z Cheng Y Gao H |
| author_facet | Hu H Li Z Cheng Y Gao H |
| author_sort | Hu H |
| collection | DOAJ |
| description | Hantong Hu,1,2,* Zengtu Li,3,* Yingying Cheng,1,2,* Hong Gao1,2 1Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou City, People’s Republic of China; 2Department of Neurobiology and Acupuncture Research, the Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou City, People’s Republic of China; 3Department of Massage, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou City, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Gao, Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, No. 219 Moganshan Road, Xihu District, Hangzhou City, People’s Republic of China, Email qtgh@vip.qq.comBackground: There is a bidirectional relationship between depression and insomnia. Depression-related insomnia is common and remains a challenging medical condition. Although acupuncture might be a potential treatment option and increasing randomized controlled trials (RCTs) have emerged, currently available evidence regarding the effect and safety of acupuncture on depression-related insomnia remains inconclusive. Thus, this protocol aims to systematically synthesize the evidence about the efficacy and safety of acupuncture for depression-related insomnia.Methods and Analysis: Eligible RCTs will be searched in nine representative databases and pooled in meta-analyses using RevMan 5.3. The methodological quality of included studies will be rated by Cochrane’s risk of bias 2.0 tool. The quality of evidence will be appraised using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. Subgroup analysis, sensitivity analyses, and publication bias will also be conducted.Discussion: This protocol outlines the planned scope and methodology for an upcoming systematic review meta-analysis, which will critically synthesize the evidence about the efficacy and safety of acupuncture on depression-related insomnia. Findings will shed light on fulfilling evidence gaps and influence evidence-based treatment decisions for clinicians in the treatment of depression-related insomnia.Keywords: acupuncture, depression-related insomnia, systematic review, meta-analysis |
| first_indexed | 2024-12-11T02:13:39Z |
| format | Article |
| id | doaj.art-d801f0d2c9a946d3abbfb864984c9fa7 |
| institution | Directory Open Access Journal |
| issn | 1178-7090 |
| language | English |
| last_indexed | 2024-12-11T02:13:39Z |
| publishDate | 2022-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Pain Research |
| spelling | doaj.art-d801f0d2c9a946d3abbfb864984c9fa72022-12-22T01:24:14ZengDove Medical PressJournal of Pain Research1178-70902022-07-01Volume 151939194776539The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-AnalysisHu HLi ZCheng YGao HHantong Hu,1,2,* Zengtu Li,3,* Yingying Cheng,1,2,* Hong Gao1,2 1Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou City, People’s Republic of China; 2Department of Neurobiology and Acupuncture Research, the Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou City, People’s Republic of China; 3Department of Massage, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou City, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hong Gao, Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University, No. 219 Moganshan Road, Xihu District, Hangzhou City, People’s Republic of China, Email qtgh@vip.qq.comBackground: There is a bidirectional relationship between depression and insomnia. Depression-related insomnia is common and remains a challenging medical condition. Although acupuncture might be a potential treatment option and increasing randomized controlled trials (RCTs) have emerged, currently available evidence regarding the effect and safety of acupuncture on depression-related insomnia remains inconclusive. Thus, this protocol aims to systematically synthesize the evidence about the efficacy and safety of acupuncture for depression-related insomnia.Methods and Analysis: Eligible RCTs will be searched in nine representative databases and pooled in meta-analyses using RevMan 5.3. The methodological quality of included studies will be rated by Cochrane’s risk of bias 2.0 tool. The quality of evidence will be appraised using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach. Subgroup analysis, sensitivity analyses, and publication bias will also be conducted.Discussion: This protocol outlines the planned scope and methodology for an upcoming systematic review meta-analysis, which will critically synthesize the evidence about the efficacy and safety of acupuncture on depression-related insomnia. Findings will shed light on fulfilling evidence gaps and influence evidence-based treatment decisions for clinicians in the treatment of depression-related insomnia.Keywords: acupuncture, depression-related insomnia, systematic review, meta-analysishttps://www.dovepress.com/the-efficacy-and-safety-of-acupuncture-for-depression-related-insomnia-peer-reviewed-fulltext-article-JPRacupuncturedepression-related insomniasystematic reviewmeta-analysis |
| spellingShingle | Hu H Li Z Cheng Y Gao H The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-Analysis Journal of Pain Research acupuncture depression-related insomnia systematic review meta-analysis |
| title | The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-Analysis |
| title_full | The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-Analysis |
| title_fullStr | The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-Analysis |
| title_full_unstemmed | The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-Analysis |
| title_short | The Efficacy and Safety of Acupuncture for Depression-Related Insomnia: Protocol for a Systematic Review and Meta-Analysis |
| title_sort | efficacy and safety of acupuncture for depression related insomnia protocol for a systematic review and meta analysis |
| topic | acupuncture depression-related insomnia systematic review meta-analysis |
| url | https://www.dovepress.com/the-efficacy-and-safety-of-acupuncture-for-depression-related-insomnia-peer-reviewed-fulltext-article-JPR |
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