Absence of ERRalpha in female mice confers resistance to bone loss induced by age or estrogen-deficiency.
BACKGROUND:ERRalpha is an orphan member of the nuclear hormone receptor superfamily, which acts as a transcription factor and is involved in various metabolic processes. ERRalpha is also highly expressed in ossification zones during mouse development as well as in human bones and cell lines. Previou...
Główni autorzy: | , , , , , , , , , , , |
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Format: | Artykuł |
Język: | English |
Wydane: |
Public Library of Science (PLoS)
2009-11-01
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Seria: | PLoS ONE |
Dostęp online: | http://europepmc.org/articles/PMC2776272?pdf=render |