Absence of ERRalpha in female mice confers resistance to bone loss induced by age or estrogen-deficiency.
BACKGROUND:ERRalpha is an orphan member of the nuclear hormone receptor superfamily, which acts as a transcription factor and is involved in various metabolic processes. ERRalpha is also highly expressed in ossification zones during mouse development as well as in human bones and cell lines. Previou...
Principais autores: | Catherine Teyssier, Marlène Gallet, Bénédicte Rabier, Laurent Monfoulet, Julien Dine, Claire Macari, Julie Espallergues, Béatrice Horard, Vincent Giguère, Martine Cohen-Solal, Olivier Chassande, Jean-Marc Vanacker |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
Public Library of Science (PLoS)
2009-11-01
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coleção: | PLoS ONE |
Acesso em linha: | http://europepmc.org/articles/PMC2776272?pdf=render |
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