Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the Dilemmas

Lymphoma is fourth most frequent malignancy diagnosed prenatally (~1:6000 cases), with Hodgkin’s Lymphoma (HL) forming the major chunk. However, in recent times, there has been an increase in occurrence of Non-Hodgkin’s Lymphoma (NHL) due to late child bearing age and high incidence of AIDS-relate...

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Main Authors: Sheeba Marwah, Harsha Shailesh Gaikwad, Ritin Mohindra, Manjula Sharma
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2017-02-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/9221/23972_CE(RA1)_F(T)_PF1(PI_RK)_PFA(RK)_PF2(MS_GH)_PF3(AG_OM).pdf
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author Sheeba Marwah
Harsha Shailesh Gaikwad
Ritin Mohindra
Manjula Sharma
author_facet Sheeba Marwah
Harsha Shailesh Gaikwad
Ritin Mohindra
Manjula Sharma
author_sort Sheeba Marwah
collection DOAJ
description Lymphoma is fourth most frequent malignancy diagnosed prenatally (~1:6000 cases), with Hodgkin’s Lymphoma (HL) forming the major chunk. However, in recent times, there has been an increase in occurrence of Non-Hodgkin’s Lymphoma (NHL) due to late child bearing age and high incidence of AIDS-related NHL in developing countries. Managing NHL in pregnancy involves intricate medical, ethical and psychological issues. Diagnostic and treatment delays may influence the prognosis for indolent cases. Seen the complexity of the management decisions associated with NHL, interdisciplinary and individualized approach becomes imperative for each woman. We present a case of 25-year-old G2P0010 at 32 weeks Period of Gestation (PoG) with right sided deep cervical lymphadenopathy, who was diagnosed as aggressive malignant NHL and was subsequently started on chemotherapy after confirmation of diagnosis and eventually had an optimal feto-maternal outcome. The critical appraisal of the accessible data, identification of controversies and unresolved issues and proposal of elucidations about varied facets of NHL in pregnancy are also provided.
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spelling doaj.art-d8062a1371cb408f8d153ee36665738e2022-12-22T01:25:20ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2017-02-01112QD03QD0510.7860/JCDR/2017/23972.9221Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the DilemmasSheeba Marwah0Harsha Shailesh Gaikwad1Ritin Mohindra2Manjula Sharma3Research Officer, Department of Obstetrics and Gynecology, Vmmc and Safdarjung Hospital, New Delhi, India.Professor, Department of Obstetrics and Gynecology, Vmmc and Safdarjung Hospital, New Delhi, India.Senior Resident, Department of Internal Medicine, Vmmc and Safdarjung Hospital, New Delhi, India.Professor and Consultant, Department of Obstetrics and Gynecology, Vmmc and Safdarjung Hospital, New Delhi, India.Lymphoma is fourth most frequent malignancy diagnosed prenatally (~1:6000 cases), with Hodgkin’s Lymphoma (HL) forming the major chunk. However, in recent times, there has been an increase in occurrence of Non-Hodgkin’s Lymphoma (NHL) due to late child bearing age and high incidence of AIDS-related NHL in developing countries. Managing NHL in pregnancy involves intricate medical, ethical and psychological issues. Diagnostic and treatment delays may influence the prognosis for indolent cases. Seen the complexity of the management decisions associated with NHL, interdisciplinary and individualized approach becomes imperative for each woman. We present a case of 25-year-old G2P0010 at 32 weeks Period of Gestation (PoG) with right sided deep cervical lymphadenopathy, who was diagnosed as aggressive malignant NHL and was subsequently started on chemotherapy after confirmation of diagnosis and eventually had an optimal feto-maternal outcome. The critical appraisal of the accessible data, identification of controversies and unresolved issues and proposal of elucidations about varied facets of NHL in pregnancy are also provided.https://jcdr.net/articles/PDF/9221/23972_CE(RA1)_F(T)_PF1(PI_RK)_PFA(RK)_PF2(MS_GH)_PF3(AG_OM).pdfchemotherapyfetusmalformationpregnancy
spellingShingle Sheeba Marwah
Harsha Shailesh Gaikwad
Ritin Mohindra
Manjula Sharma
Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the Dilemmas
Journal of Clinical and Diagnostic Research
chemotherapy
fetus
malformation
pregnancy
title Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the Dilemmas
title_full Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the Dilemmas
title_fullStr Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the Dilemmas
title_full_unstemmed Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the Dilemmas
title_short Up the Duff With Non-Hodgkin’s Lymphoma: The Traumas and the Dilemmas
title_sort up the duff with non hodgkin s lymphoma the traumas and the dilemmas
topic chemotherapy
fetus
malformation
pregnancy
url https://jcdr.net/articles/PDF/9221/23972_CE(RA1)_F(T)_PF1(PI_RK)_PFA(RK)_PF2(MS_GH)_PF3(AG_OM).pdf
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AT ritinmohindra uptheduffwithnonhodgkinslymphomathetraumasandthedilemmas
AT manjulasharma uptheduffwithnonhodgkinslymphomathetraumasandthedilemmas