Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman
General and stereoselective synthesis of tetracyclic isochroman-containing polyketide oligomers is challenging. Here, the authors report on an Au(I)/chiral Sc(III) bimetallic catalyst for a biomimetic asymmetric hetero-Diels–Alder reaction for in-situ generation of isochromene and ortho-quinonemethi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-25198-y |
| _version_ | 1818843970614067200 |
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| author | Xiangfeng Lin Xianghui Liu Kai Wang Qian Li Yan Liu Can Li |
| author_facet | Xiangfeng Lin Xianghui Liu Kai Wang Qian Li Yan Liu Can Li |
| author_sort | Xiangfeng Lin |
| collection | DOAJ |
| description | General and stereoselective synthesis of tetracyclic isochroman-containing polyketide oligomers is challenging. Here, the authors report on an Au(I)/chiral Sc(III) bimetallic catalyst for a biomimetic asymmetric hetero-Diels–Alder reaction for in-situ generation of isochromene and ortho-quinonemethide. |
| first_indexed | 2024-12-19T05:06:20Z |
| format | Article |
| id | doaj.art-d8067b9568c34fa380fcc342497aa73e |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T05:06:20Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-d8067b9568c34fa380fcc342497aa73e2022-12-21T20:34:56ZengNature PortfolioNature Communications2041-17232021-08-011211910.1038/s41467-021-25198-yBiomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochromanXiangfeng Lin0Xianghui Liu1Kai Wang2Qian Li3Yan Liu4Can Li5State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of SciencesState Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of SciencesState Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of SciencesState Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of SciencesState Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of SciencesState Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of SciencesGeneral and stereoselective synthesis of tetracyclic isochroman-containing polyketide oligomers is challenging. Here, the authors report on an Au(I)/chiral Sc(III) bimetallic catalyst for a biomimetic asymmetric hetero-Diels–Alder reaction for in-situ generation of isochromene and ortho-quinonemethide.https://doi.org/10.1038/s41467-021-25198-y |
| spellingShingle | Xiangfeng Lin Xianghui Liu Kai Wang Qian Li Yan Liu Can Li Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman Nature Communications |
| title | Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman |
| title_full | Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman |
| title_fullStr | Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman |
| title_full_unstemmed | Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman |
| title_short | Biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman |
| title_sort | biomimetic approach to the catalytic enantioselective synthesis of tetracyclic isochroman |
| url | https://doi.org/10.1038/s41467-021-25198-y |
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