Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites

Background. Vascular cell adhesion molecule-1 (VCAM-1) is associated with ovarian cancer progression but the origin of its soluble form (sVCAM-1) in serum is not well investigated. The purpose of this study was to elucidate whether the concentration of sVCAM-1 in serum correlates with the concentrat...

Full description

Bibliographic Details
Main Authors: Jakimovska Marina, Cerne Katarina, Verdenik Ivan, Kobal Borut
Format: Article
Language:English
Published: Sciendo 2014-09-01
Series:Radiology and Oncology
Subjects:
Online Access:https://doi.org/10.2478/raon-2013-0066
_version_ 1818729635225010176
author Jakimovska Marina
Cerne Katarina
Verdenik Ivan
Kobal Borut
author_facet Jakimovska Marina
Cerne Katarina
Verdenik Ivan
Kobal Borut
author_sort Jakimovska Marina
collection DOAJ
description Background. Vascular cell adhesion molecule-1 (VCAM-1) is associated with ovarian cancer progression but the origin of its soluble form (sVCAM-1) in serum is not well investigated. The purpose of this study was to elucidate whether the concentration of sVCAM-1 in serum correlates with the concentration in ascites, that represents local tumour environment, and with systemic inflammation, various clinicopathological characteristics, and patient outcome.
first_indexed 2024-12-17T22:49:01Z
format Article
id doaj.art-d806fc4dca984fe38cdffe27c1f48acc
institution Directory Open Access Journal
issn 1581-3207
language English
last_indexed 2024-12-17T22:49:01Z
publishDate 2014-09-01
publisher Sciendo
record_format Article
series Radiology and Oncology
spelling doaj.art-d806fc4dca984fe38cdffe27c1f48acc2022-12-21T21:29:44ZengSciendoRadiology and Oncology1581-32072014-09-0148330731310.2478/raon-2013-0066raon-2013-0066Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascitesJakimovska Marina0Cerne Katarina1Verdenik Ivan2Kobal Borut3Department of Obstetrics and Gynaecology University Medical Centre, Ljubljana, SloveniaDepartment of Pharmacology and Experimental Toxicology, Faculty of Medicine, University of Ljubljana, Ljubljana, SloveniaDepartment of Obstetrics and Gynaecology University Medical Centre, Ljubljana, SloveniaDepartment of Obstetrics and Gynaecology University Medical Centre, Ljubljana, SloveniaBackground. Vascular cell adhesion molecule-1 (VCAM-1) is associated with ovarian cancer progression but the origin of its soluble form (sVCAM-1) in serum is not well investigated. The purpose of this study was to elucidate whether the concentration of sVCAM-1 in serum correlates with the concentration in ascites, that represents local tumour environment, and with systemic inflammation, various clinicopathological characteristics, and patient outcome.https://doi.org/10.2478/raon-2013-0066svcam-1ovarian cancerflow cytometry
spellingShingle Jakimovska Marina
Cerne Katarina
Verdenik Ivan
Kobal Borut
Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites
Radiology and Oncology
svcam-1
ovarian cancer
flow cytometry
title Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites
title_full Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites
title_fullStr Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites
title_full_unstemmed Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites
title_short Circulating serum sVCAM-1 concentration in advanced ovarian cancer patients: correlation with concentration in ascites
title_sort circulating serum svcam 1 concentration in advanced ovarian cancer patients correlation with concentration in ascites
topic svcam-1
ovarian cancer
flow cytometry
url https://doi.org/10.2478/raon-2013-0066
work_keys_str_mv AT jakimovskamarina circulatingserumsvcam1concentrationinadvancedovariancancerpatientscorrelationwithconcentrationinascites
AT cernekatarina circulatingserumsvcam1concentrationinadvancedovariancancerpatientscorrelationwithconcentrationinascites
AT verdenikivan circulatingserumsvcam1concentrationinadvancedovariancancerpatientscorrelationwithconcentrationinascites
AT kobalborut circulatingserumsvcam1concentrationinadvancedovariancancerpatientscorrelationwithconcentrationinascites