<i>In Situ</i> Crosslinked Hydrogel Depot for Sustained Antibody Release Improves Immune Checkpoint Blockade Cancer Immunotherapy

<i>In Situ</i> Crosslinked Hydrogel Depot for Sustained Antibody Release Improves Immune Checkpoint Blockade Cancer Immunotherapy

The therapeutic inhibition of immune checkpoints, including cytotoxic T lymphocyte-associated protein (CTLA)-4 and programmed cell death 1 (PD-1), through the use of function blocking antibodies can confer improved clinical outcomes by invigorating CD8<sup>+</sup> T cell-mediated antican...

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Bibliographic Details
Main Authors:	Jihoon Kim, David M. Francis, Susan N. Thomas
Format:	Article
Language:	English
Published:	MDPI AG 2021-02-01
Series:	Nanomaterials
Subjects:	intradermal immunotherapy immune checkpoint blockades sustained release <i>in situ</i> crosslinked hydrogel
Online Access:	https://www.mdpi.com/2079-4991/11/2/471

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