Intraparenchymal breast leiomyoma and atypical leiomyoma
Abstract Background Breast leiomyoma is a rare benign mesenchymal tumor, accounting for less than 1% of all breast neoplasms. Cases of breast atypical leiomyoma is even more rarely reported and its diagnostic criteria together with its clinical courses is not cleared defined. Case presentation We de...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-04-01
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| Series: | BMC Women's Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12905-022-01700-6 |
| _version_ | 1818273901590872064 |
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| author | Mengping Long Xuejiao Lina Hu Guiyang Zhao Yiqiang Liu Taobo Hu |
| author_facet | Mengping Long Xuejiao Lina Hu Guiyang Zhao Yiqiang Liu Taobo Hu |
| author_sort | Mengping Long |
| collection | DOAJ |
| description | Abstract Background Breast leiomyoma is a rare benign mesenchymal tumor, accounting for less than 1% of all breast neoplasms. Cases of breast atypical leiomyoma is even more rarely reported and its diagnostic criteria together with its clinical courses is not cleared defined. Case presentation We described two patients with breast leiomyomas. One has unilateral benign breast leiomyoma, the other one has bilateral breast leiomyomas. For the bilateral case, the left-side tumor was diagnosed as benign leiomyoma while the right-side tumor was diagnosed as atypical leiomyoma. The morphological features that lead to the diagnosis of atypical leiomyoma are its invasive growth pattern, mild nuclear atypia, and mitotic figures up to 3mitoses/10HPF. Conclusions Atypical breast leiomyoma appears to behave like benign leiomyoma without recurrence in our study with nine-year follow-up. Due to the limited experience, cases presented as atypical intraparenchymal breast leiomyoma should be closely followed. |
| first_indexed | 2024-12-12T22:05:20Z |
| format | Article |
| id | doaj.art-d80a345a6809459d80032cbc0019d613 |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-12-12T22:05:20Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-d80a345a6809459d80032cbc0019d6132022-12-22T00:10:24ZengBMCBMC Women's Health1472-68742022-04-012211410.1186/s12905-022-01700-6Intraparenchymal breast leiomyoma and atypical leiomyomaMengping Long0Xuejiao Lina Hu1Guiyang Zhao2Yiqiang Liu3Taobo Hu4Department of Pathology, Peking University Cancer HospitalDepartment of Pathology, Alaska Native Medical CenterDepartment of Oncology, Beijing Changping HospitalDepartment of Pathology, Peking University Cancer HospitalDepartment of Breast Surgery, Peking University People’s HospitalAbstract Background Breast leiomyoma is a rare benign mesenchymal tumor, accounting for less than 1% of all breast neoplasms. Cases of breast atypical leiomyoma is even more rarely reported and its diagnostic criteria together with its clinical courses is not cleared defined. Case presentation We described two patients with breast leiomyomas. One has unilateral benign breast leiomyoma, the other one has bilateral breast leiomyomas. For the bilateral case, the left-side tumor was diagnosed as benign leiomyoma while the right-side tumor was diagnosed as atypical leiomyoma. The morphological features that lead to the diagnosis of atypical leiomyoma are its invasive growth pattern, mild nuclear atypia, and mitotic figures up to 3mitoses/10HPF. Conclusions Atypical breast leiomyoma appears to behave like benign leiomyoma without recurrence in our study with nine-year follow-up. Due to the limited experience, cases presented as atypical intraparenchymal breast leiomyoma should be closely followed.https://doi.org/10.1186/s12905-022-01700-6Breast leiomyomaAtypical leiomyomaCase report |
| spellingShingle | Mengping Long Xuejiao Lina Hu Guiyang Zhao Yiqiang Liu Taobo Hu Intraparenchymal breast leiomyoma and atypical leiomyoma BMC Women's Health Breast leiomyoma Atypical leiomyoma Case report |
| title | Intraparenchymal breast leiomyoma and atypical leiomyoma |
| title_full | Intraparenchymal breast leiomyoma and atypical leiomyoma |
| title_fullStr | Intraparenchymal breast leiomyoma and atypical leiomyoma |
| title_full_unstemmed | Intraparenchymal breast leiomyoma and atypical leiomyoma |
| title_short | Intraparenchymal breast leiomyoma and atypical leiomyoma |
| title_sort | intraparenchymal breast leiomyoma and atypical leiomyoma |
| topic | Breast leiomyoma Atypical leiomyoma Case report |
| url | https://doi.org/10.1186/s12905-022-01700-6 |
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