A Case of Eosinophilic Pustular Folliculitis since Birth
A newborn male infant presented with multiple pustules and erosions with erythema involving his scalp and forehead at birth. One week after birth, new pustules continued to appear, forming crusted, ring-shaped plaques with pigmentation. Tests for possible pathogens were negative. Tzanck smear and sk...
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| Format: | Article |
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MDPI AG
2021-01-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/8/1/30 |
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| author | Satoshi Yoshida Kazuki Yatsuzuka Kenji Chigyo Yuta Kuroo Koji Takemoto Koji Sayama |
| author_facet | Satoshi Yoshida Kazuki Yatsuzuka Kenji Chigyo Yuta Kuroo Koji Takemoto Koji Sayama |
| author_sort | Satoshi Yoshida |
| collection | DOAJ |
| description | A newborn male infant presented with multiple pustules and erosions with erythema involving his scalp and forehead at birth. One week after birth, new pustules continued to appear, forming crusted, ring-shaped plaques with pigmentation. Tests for possible pathogens were negative. Tzanck smear and skin biopsy revealed pustules beneath the stratum corneum at sites corresponding to hair follicles, which contained eosinophils and neutrophils. Taken together, a diagnosis of eosinophilic pustular folliculitis (EPF) was made. The pustules on the head disappeared rapidly with topical corticosteroid treatment, although new eruptions were still observed on the trunk about one month after birth. To our knowledge, only two cases of EPF since birth have been reported to date. Here, we also discuss the differential diagnosis of noninfectious pustular diseases at birth, including erythema toxicum neonatorum and transient neonatal pustular melanosis. These diseases, and EPF, may present with very similar clinical symptoms at birth, and the Tzanck test or biopsy may be required for differential diagnosis. |
| first_indexed | 2024-03-09T05:48:34Z |
| format | Article |
| id | doaj.art-d812b9019c704d41ab61b69e518bab0e |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T05:48:34Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-d812b9019c704d41ab61b69e518bab0e2023-12-03T12:19:36ZengMDPI AGChildren2227-90672021-01-01813010.3390/children8010030A Case of Eosinophilic Pustular Folliculitis since BirthSatoshi Yoshida0Kazuki Yatsuzuka1Kenji Chigyo2Yuta Kuroo3Koji Takemoto4Koji Sayama5Department of Dermatology, Ehime University Graduate School of Medicine, Ehime 791-0295, JapanDepartment of Dermatology, Ehime University Graduate School of Medicine, Ehime 791-0295, JapanDepartment of Pediatrics, Ehime Prefectural Niihama Hospital, Ehime 792-0042, JapanDepartment of Dermatology, Ehime University Graduate School of Medicine, Ehime 791-0295, JapanDepartment of Pediatrics, Ehime Prefectural Niihama Hospital, Ehime 792-0042, JapanDepartment of Dermatology, Ehime University Graduate School of Medicine, Ehime 791-0295, JapanA newborn male infant presented with multiple pustules and erosions with erythema involving his scalp and forehead at birth. One week after birth, new pustules continued to appear, forming crusted, ring-shaped plaques with pigmentation. Tests for possible pathogens were negative. Tzanck smear and skin biopsy revealed pustules beneath the stratum corneum at sites corresponding to hair follicles, which contained eosinophils and neutrophils. Taken together, a diagnosis of eosinophilic pustular folliculitis (EPF) was made. The pustules on the head disappeared rapidly with topical corticosteroid treatment, although new eruptions were still observed on the trunk about one month after birth. To our knowledge, only two cases of EPF since birth have been reported to date. Here, we also discuss the differential diagnosis of noninfectious pustular diseases at birth, including erythema toxicum neonatorum and transient neonatal pustular melanosis. These diseases, and EPF, may present with very similar clinical symptoms at birth, and the Tzanck test or biopsy may be required for differential diagnosis.https://www.mdpi.com/2227-9067/8/1/30eosinophilic pustular folliculitistransient neonatal pustular melanosiserythema toxicum neonatorumneonatal eosinophilic pustulosis |
| spellingShingle | Satoshi Yoshida Kazuki Yatsuzuka Kenji Chigyo Yuta Kuroo Koji Takemoto Koji Sayama A Case of Eosinophilic Pustular Folliculitis since Birth Children eosinophilic pustular folliculitis transient neonatal pustular melanosis erythema toxicum neonatorum neonatal eosinophilic pustulosis |
| title | A Case of Eosinophilic Pustular Folliculitis since Birth |
| title_full | A Case of Eosinophilic Pustular Folliculitis since Birth |
| title_fullStr | A Case of Eosinophilic Pustular Folliculitis since Birth |
| title_full_unstemmed | A Case of Eosinophilic Pustular Folliculitis since Birth |
| title_short | A Case of Eosinophilic Pustular Folliculitis since Birth |
| title_sort | case of eosinophilic pustular folliculitis since birth |
| topic | eosinophilic pustular folliculitis transient neonatal pustular melanosis erythema toxicum neonatorum neonatal eosinophilic pustulosis |
| url | https://www.mdpi.com/2227-9067/8/1/30 |
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