Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation
Background/Objective: About 20% of biliary atresia (BA) survivors have attacks of esophageal variceal bleeding. We propose a method to evaluate the risk of esophageal variceal bleeding (EVB) using noninvasive indices by multislice computed tomography (CT). Methods: We reviewed 31 potential living-re...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2011-10-01
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| Series: | Asian Journal of Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1015958411000182 |
| _version_ | 1819268381526720512 |
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| author | Cheng-Ta Yang Huey-Ling Chen Ming Chih Ho Steven Shinn-Forng Peng |
| author_facet | Cheng-Ta Yang Huey-Ling Chen Ming Chih Ho Steven Shinn-Forng Peng |
| author_sort | Cheng-Ta Yang |
| collection | DOAJ |
| description | Background/Objective: About 20% of biliary atresia (BA) survivors have attacks of esophageal variceal bleeding. We propose a method to evaluate the risk of esophageal variceal bleeding (EVB) using noninvasive indices by multislice computed tomography (CT).
Methods: We reviewed 31 potential living-related liver recipients aged 99–5314 days (mean, 1474 days) who underwent CT examinations using a 64-slice multislice CT scanner. Of the 31 patients, 19 patients (Group A) with fecal occult blood had EVB on esophagogastroduodenoscopy; the rest belonged to Group B. Splenic diameters (mm) were divided by body heights (m) and platelet counts (1000/mm3) to produce standardized ratios of transverse splenic length/body height/platelet count (SLHPR). The transverse diameters of paraesophageal veins (PVs) and perigastric veins (PGVs) were measured adjacent to the lower thoracic esophagus and within the lesser sac, respectively.
Results: According to a receiver operating characteristic curve analysis, the SLHPRs (r=0.833), transverse PV (r=0.957), and PGV (r=0.987) diameters were better predictors of EVB than demographic and laboratory variables. However, the transverse diameters of PGVs and PVs were the most accurate predictors of the EVB.
Conclusion: For candidates awaiting liver transplantation, screening by noninvasive SLHPR and the transverse diameters of PGVs and PVs by CT may help to identify BA patients with a high risk of EVB. |
| first_indexed | 2024-12-23T21:32:10Z |
| format | Article |
| id | doaj.art-d817b76632c3450bafc6fa0d5be119fa |
| institution | Directory Open Access Journal |
| issn | 1015-9584 |
| language | English |
| last_indexed | 2024-12-23T21:32:10Z |
| publishDate | 2011-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Surgery |
| spelling | doaj.art-d817b76632c3450bafc6fa0d5be119fa2022-12-21T17:30:26ZengElsevierAsian Journal of Surgery1015-95842011-10-0134416817410.1016/j.asjsur.2011.11.006Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantationCheng-Ta Yang0Huey-Ling Chen1Ming Chih Ho2Steven Shinn-Forng Peng3Department of Medical Imaging, National Taiwan University Hospital and Medical School, Taipei, Taiwan, ROCDepartment of Pediatrics, National Taiwan University Hospital and Medical School, Taipei, Taiwan, ROCDepartment of Surgery, National Taiwan University Hospital and Medical School, Taipei, Taiwan, ROCDepartment of Medical Imaging, National Taiwan University Hospital and Medical School, Taipei, Taiwan, ROCBackground/Objective: About 20% of biliary atresia (BA) survivors have attacks of esophageal variceal bleeding. We propose a method to evaluate the risk of esophageal variceal bleeding (EVB) using noninvasive indices by multislice computed tomography (CT). Methods: We reviewed 31 potential living-related liver recipients aged 99–5314 days (mean, 1474 days) who underwent CT examinations using a 64-slice multislice CT scanner. Of the 31 patients, 19 patients (Group A) with fecal occult blood had EVB on esophagogastroduodenoscopy; the rest belonged to Group B. Splenic diameters (mm) were divided by body heights (m) and platelet counts (1000/mm3) to produce standardized ratios of transverse splenic length/body height/platelet count (SLHPR). The transverse diameters of paraesophageal veins (PVs) and perigastric veins (PGVs) were measured adjacent to the lower thoracic esophagus and within the lesser sac, respectively. Results: According to a receiver operating characteristic curve analysis, the SLHPRs (r=0.833), transverse PV (r=0.957), and PGV (r=0.987) diameters were better predictors of EVB than demographic and laboratory variables. However, the transverse diameters of PGVs and PVs were the most accurate predictors of the EVB. Conclusion: For candidates awaiting liver transplantation, screening by noninvasive SLHPR and the transverse diameters of PGVs and PVs by CT may help to identify BA patients with a high risk of EVB.http://www.sciencedirect.com/science/article/pii/S1015958411000182biliary atresiachildrencomputed tomographyesophageal varices |
| spellingShingle | Cheng-Ta Yang Huey-Ling Chen Ming Chih Ho Steven Shinn-Forng Peng Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation Asian Journal of Surgery biliary atresia children computed tomography esophageal varices |
| title | Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation |
| title_full | Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation |
| title_fullStr | Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation |
| title_full_unstemmed | Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation |
| title_short | Computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation |
| title_sort | computed tomography indices and criteria for the prediction of esophageal variceal bleeding in survivors of biliary atresia awaiting liver transplantation |
| topic | biliary atresia children computed tomography esophageal varices |
| url | http://www.sciencedirect.com/science/article/pii/S1015958411000182 |
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