Regulation of Cell Adhesion and Migration via Microtubule Cytoskeleton Organization, Cell Polarity, and Phosphoinositide Signaling

Regulation of Cell Adhesion and Migration via Microtubule Cytoskeleton Organization, Cell Polarity, and Phosphoinositide Signaling

The capacity for cancer cells to metastasize to distant organs depends on their ability to execute the carefully choreographed processes of cell adhesion and migration. As most human cancers are of epithelial origin (carcinoma), the transcriptional downregulation of adherent/tight junction proteins...

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Bibliographic Details
Main Authors: Narendra Thapa, Tianmu Wen, Vincent L. Cryns, Richard A. Anderson
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biomolecules
Subjects:
phosphoinositide
microtubules
cell polarity
epithelial cell
mesenchymal cells
cell adhesion
Online Access:https://www.mdpi.com/2218-273X/13/10/1430

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