Use of High-Dose Nebulized Colistimethate in Patients with Colistin-Only Susceptible <i>Acinetobacter baumannii</i> VAP: Clinical, Pharmacokinetic and Microbiome Features

Use of High-Dose Nebulized Colistimethate in Patients with Colistin-Only Susceptible <i>Acinetobacter baumannii</i> VAP: Clinical, Pharmacokinetic and Microbiome Features

(1) Background: Colistin-only susceptible (COS) <i>Acinetobacter baumannii</i> (AB) ventilator-associated pneumonia (VAP) represents a clinical challenge in the Intensive Care Unit (ICU) due to the negligible lung diffusion of this molecule and the low-grade evidence on efficacy of its n...

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Bibliographic Details
Main Authors: Gennaro De Pascale, Gabriele Pintaudi, Lucia Lisi, Flavio De Maio, Salvatore Lucio Cutuli, Eloisa Sofia Tanzarella, Simone Carelli, Gianmarco Lombardi, Melania Cesarano, Veronica Gennenzi, Gabriella Maria Pia Ciotti, Domenico Luca Grieco, Brunella Posteraro, Maurizio Sanguinetti, Pierluigi Navarra, Massimo Antonelli
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Antibiotics
Subjects:
colistin
nebulization
ventilator-associated pneumonia
<i>Acinetobacter baumannii</i>
Online Access:https://www.mdpi.com/2079-6382/12/1/125

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https://www.mdpi.com/2079-6382/12/1/125

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