Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients

Heart disease: Links to oral bacteria A review of bacterial populations in the mouth and in diseased arteries will help research into the role of bacteria in heart disease. Amit Sharma and colleagues at the International Centre for Genetic Engineering and Biotechnology, with co-workers at the All In...

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Main Authors: Jyoti Chhibber-Goel, Varsha Singhal, Debaleena Bhowmik, Rahul Vivek, Neeraj Parakh, Balram Bhargava, Amit Sharma
Format: Article
Language:English
Published: Nature Portfolio 2016-12-01
Series:npj Biofilms and Microbiomes
Online Access:https://doi.org/10.1038/s41522-016-0009-7
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author Jyoti Chhibber-Goel
Varsha Singhal
Debaleena Bhowmik
Rahul Vivek
Neeraj Parakh
Balram Bhargava
Amit Sharma
author_facet Jyoti Chhibber-Goel
Varsha Singhal
Debaleena Bhowmik
Rahul Vivek
Neeraj Parakh
Balram Bhargava
Amit Sharma
author_sort Jyoti Chhibber-Goel
collection DOAJ
description Heart disease: Links to oral bacteria A review of bacterial populations in the mouth and in diseased arteries will help research into the role of bacteria in heart disease. Amit Sharma and colleagues at the International Centre for Genetic Engineering and Biotechnology, with co-workers at the All India Institute of Medical Sciences, both in New Delhi, India, analyzed 63 studies covering 1791 patients spread over a decade. They summarize evidence of 23 types of oral bacteria that are also found in atherosclerotic plaques in artery walls. The review also cataloged the proteins secreted by the bacteria and discussed possible involvement of these proteins in the migration of bacteria through the bloodstream. Full genetic details are available for 19 of the 23 bacterial species, which should greatly assist further investigations into the significance of bacteria in the onset of heart disease.
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spelling doaj.art-d822ee8878084d09b93b516e11bb0c912022-12-21T21:53:11ZengNature Portfolionpj Biofilms and Microbiomes2055-50082016-12-012111310.1038/s41522-016-0009-7Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patientsJyoti Chhibber-Goel0Varsha Singhal1Debaleena Bhowmik2Rahul Vivek3Neeraj Parakh4Balram Bhargava5Amit Sharma6Molecular Medicine Group, International Centre for Genetic Engineering and BiotechnologyMolecular Medicine Group, International Centre for Genetic Engineering and BiotechnologyMolecular Medicine Group, International Centre for Genetic Engineering and BiotechnologyMolecular Medicine Group, International Centre for Genetic Engineering and BiotechnologyCardiothoracic Sciences Centre, All India Institute of Medical SciencesCardiothoracic Sciences Centre, All India Institute of Medical SciencesMolecular Medicine Group, International Centre for Genetic Engineering and BiotechnologyHeart disease: Links to oral bacteria A review of bacterial populations in the mouth and in diseased arteries will help research into the role of bacteria in heart disease. Amit Sharma and colleagues at the International Centre for Genetic Engineering and Biotechnology, with co-workers at the All India Institute of Medical Sciences, both in New Delhi, India, analyzed 63 studies covering 1791 patients spread over a decade. They summarize evidence of 23 types of oral bacteria that are also found in atherosclerotic plaques in artery walls. The review also cataloged the proteins secreted by the bacteria and discussed possible involvement of these proteins in the migration of bacteria through the bloodstream. Full genetic details are available for 19 of the 23 bacterial species, which should greatly assist further investigations into the significance of bacteria in the onset of heart disease.https://doi.org/10.1038/s41522-016-0009-7
spellingShingle Jyoti Chhibber-Goel
Varsha Singhal
Debaleena Bhowmik
Rahul Vivek
Neeraj Parakh
Balram Bhargava
Amit Sharma
Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients
npj Biofilms and Microbiomes
title Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients
title_full Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients
title_fullStr Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients
title_full_unstemmed Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients
title_short Linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients
title_sort linkages between oral commensal bacteria and atherosclerotic plaques in coronary artery disease patients
url https://doi.org/10.1038/s41522-016-0009-7
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