On the Origin and Evolutionary Relationships of the Reverse Transcriptases Associated With Type III CRISPR-Cas Systems

On the Origin and Evolutionary Relationships of the Reverse Transcriptases Associated With Type III CRISPR-Cas Systems

Reverse transcriptases (RTs) closely related to those encoded by group II introns but lacking the intron RNA structure have been found associated with type III clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems, a prokaryotic immune system against invading viruses and for...

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Bibliographic Details
Main Authors: Nicolás Toro, Francisco Martínez-Abarca, Alejandro González-Delgado, Mario Rodríguez Mestre
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
Cas1
CRISPR-Cas system
genome evolution
group II introns
retroelements
reverse transcriptase
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01317/full

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