Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety

In this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physi...

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Main Authors: Masomeh Eskandari, Abraham F. Jalbout, Aliasghar Jarrahpour
Format: Article
Language:English
Published: MDPI AG 2007-05-01
Series:Molbank
Subjects:
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author Masomeh Eskandari
Abraham F. Jalbout
Aliasghar Jarrahpour
author_facet Masomeh Eskandari
Abraham F. Jalbout
Aliasghar Jarrahpour
author_sort Masomeh Eskandari
collection DOAJ
description In this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physical properties of the molecule.
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spelling doaj.art-d827aee4cabe43788c51faf038280d7a2022-12-22T00:36:32ZengMDPI AGMolbank1422-85992007-05-0120072M54210.3390/M542Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino MoietyMasomeh EskandariAbraham F. JalboutAliasghar JarrahpourIn this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physical properties of the molecule.Azetidine-2-oneN-morpholinopropyl monocyclic β-lactamStaudinger reactionAM1
spellingShingle Masomeh Eskandari
Abraham F. Jalbout
Aliasghar Jarrahpour
Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety
Molbank
Azetidine-2-one
N-morpholinopropyl monocyclic β-lactam
Staudinger reaction
AM1
title Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety
title_full Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety
title_fullStr Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety
title_full_unstemmed Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety
title_short Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety
title_sort synthesis and physical characterization of e 1 3 morpholinopropyl 3 phenoxy 4 styrylazetidine 2 one as the first β lactam bearing a morpholino moiety
topic Azetidine-2-one
N-morpholinopropyl monocyclic β-lactam
Staudinger reaction
AM1
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AT abrahamfjalbout synthesisandphysicalcharacterizationofe13morpholinopropyl3phenoxy4styrylazetidine2oneasthefirstblactambearingamorpholinomoiety
AT aliasgharjarrahpour synthesisandphysicalcharacterizationofe13morpholinopropyl3phenoxy4styrylazetidine2oneasthefirstblactambearingamorpholinomoiety