Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety
In this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physi...
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MDPI AG
2007-05-01
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author | Masomeh Eskandari Abraham F. Jalbout Aliasghar Jarrahpour |
author_facet | Masomeh Eskandari Abraham F. Jalbout Aliasghar Jarrahpour |
author_sort | Masomeh Eskandari |
collection | DOAJ |
description | In this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physical properties of the molecule. |
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id | doaj.art-d827aee4cabe43788c51faf038280d7a |
institution | Directory Open Access Journal |
issn | 1422-8599 |
language | English |
last_indexed | 2024-12-12T05:23:49Z |
publishDate | 2007-05-01 |
publisher | MDPI AG |
record_format | Article |
series | Molbank |
spelling | doaj.art-d827aee4cabe43788c51faf038280d7a2022-12-22T00:36:32ZengMDPI AGMolbank1422-85992007-05-0120072M54210.3390/M542Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino MoietyMasomeh EskandariAbraham F. JalboutAliasghar JarrahpourIn this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physical properties of the molecule.Azetidine-2-oneN-morpholinopropyl monocyclic β-lactamStaudinger reactionAM1 |
spellingShingle | Masomeh Eskandari Abraham F. Jalbout Aliasghar Jarrahpour Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety Molbank Azetidine-2-one N-morpholinopropyl monocyclic β-lactam Staudinger reaction AM1 |
title | Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety |
title_full | Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety |
title_fullStr | Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety |
title_full_unstemmed | Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety |
title_short | Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety |
title_sort | synthesis and physical characterization of e 1 3 morpholinopropyl 3 phenoxy 4 styrylazetidine 2 one as the first β lactam bearing a morpholino moiety |
topic | Azetidine-2-one N-morpholinopropyl monocyclic β-lactam Staudinger reaction AM1 |
work_keys_str_mv | AT masomeheskandari synthesisandphysicalcharacterizationofe13morpholinopropyl3phenoxy4styrylazetidine2oneasthefirstblactambearingamorpholinomoiety AT abrahamfjalbout synthesisandphysicalcharacterizationofe13morpholinopropyl3phenoxy4styrylazetidine2oneasthefirstblactambearingamorpholinomoiety AT aliasgharjarrahpour synthesisandphysicalcharacterizationofe13morpholinopropyl3phenoxy4styrylazetidine2oneasthefirstblactambearingamorpholinomoiety |