Protochlamydia naegleriophila as Etiologic Agent of Pneumonia
Using ameba coculture, we grew a Naegleria endosymbiont. Phenotypic, genetic, and phylogenetic analyses supported its affiliation as Protochlamydia naegleriophila sp. nov. We then developed a specific diagnostic PCR for Protochlamydia spp. When applied to bronchoalveolar lavages, results of this PCR...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2008-01-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/14/1/07-0980_article |
| _version_ | 1811341128357642240 |
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| author | Nicola Casson Rolf Michel Karl-Dieter Müller John David Aubert Gilbert Greub |
| author_facet | Nicola Casson Rolf Michel Karl-Dieter Müller John David Aubert Gilbert Greub |
| author_sort | Nicola Casson |
| collection | DOAJ |
| description | Using ameba coculture, we grew a Naegleria endosymbiont. Phenotypic, genetic, and phylogenetic analyses supported its affiliation as Protochlamydia naegleriophila sp. nov. We then developed a specific diagnostic PCR for Protochlamydia spp. When applied to bronchoalveolar lavages, results of this PCR were positive for 1 patient with pneumonia. Further studies are needed to assess the role of Protochlamydia spp. in pneumonia. |
| first_indexed | 2024-04-13T18:52:10Z |
| format | Article |
| id | doaj.art-d8280265a0d748d391d21adb0e8baf66 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-13T18:52:10Z |
| publishDate | 2008-01-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-d8280265a0d748d391d21adb0e8baf662022-12-22T02:34:23ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592008-01-0114116817210.3201/eid1401.070980Protochlamydia naegleriophila as Etiologic Agent of PneumoniaNicola CassonRolf MichelKarl-Dieter MüllerJohn David AubertGilbert GreubUsing ameba coculture, we grew a Naegleria endosymbiont. Phenotypic, genetic, and phylogenetic analyses supported its affiliation as Protochlamydia naegleriophila sp. nov. We then developed a specific diagnostic PCR for Protochlamydia spp. When applied to bronchoalveolar lavages, results of this PCR were positive for 1 patient with pneumonia. Further studies are needed to assess the role of Protochlamydia spp. in pneumonia.https://wwwnc.cdc.gov/eid/article/14/1/07-0980_articleObligate intracellular bacteriachlamydia-like organismspathogenicitypneumoniaTaqMan PCRchlamydiae |
| spellingShingle | Nicola Casson Rolf Michel Karl-Dieter Müller John David Aubert Gilbert Greub Protochlamydia naegleriophila as Etiologic Agent of Pneumonia Emerging Infectious Diseases Obligate intracellular bacteria chlamydia-like organisms pathogenicity pneumonia TaqMan PCR chlamydiae |
| title | Protochlamydia naegleriophila as Etiologic Agent of Pneumonia |
| title_full | Protochlamydia naegleriophila as Etiologic Agent of Pneumonia |
| title_fullStr | Protochlamydia naegleriophila as Etiologic Agent of Pneumonia |
| title_full_unstemmed | Protochlamydia naegleriophila as Etiologic Agent of Pneumonia |
| title_short | Protochlamydia naegleriophila as Etiologic Agent of Pneumonia |
| title_sort | protochlamydia naegleriophila as etiologic agent of pneumonia |
| topic | Obligate intracellular bacteria chlamydia-like organisms pathogenicity pneumonia TaqMan PCR chlamydiae |
| url | https://wwwnc.cdc.gov/eid/article/14/1/07-0980_article |
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