Impaired Expression of GABA Signaling Components in the Alzheimer’s Disease Middle Temporal Gyrus

Impaired Expression of GABA Signaling Components in the Alzheimer’s Disease Middle Temporal Gyrus

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter, playing a central role in the regulation of cortical excitability and the maintenance of the excitatory/inhibitory (E/I) balance. Several lines of evidence point to a remodeling of the cerebral GABAergic system in Alzheimer’s dis...

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Bibliographic Details
Main Authors: Karan Govindpani, Clinton Turner, Henry J. Waldvogel, Richard L. M. Faull, Andrea Kwakowsky
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
GABA
GABAergic system
GABA receptors
GABA transporters
middle temporal gyrus
Online Access:https://www.mdpi.com/1422-0067/21/22/8704

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