Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance

Abstract Background An O-ring gantry-type linear accelerator (LINAC) with a 6-MV flattening filter-free (FFF) photon beam, Halcyon, includes a reference beam that contains representative information such as the percent depth dose, profile and output factor for commissioning and quality assurance. Ho...

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Main Authors: Min-Geon Choi, Martin Law, Do-Kun Yoon, Mikoto Tamura, Kenji Matsumoto, Masakazu Otsuka, Moo-Sub Kim, Shih-Kien Djeng, Hajime Monzen, Tae Suk Suh
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Radiation Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13014-020-01709-x
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author Min-Geon Choi
Martin Law
Do-Kun Yoon
Mikoto Tamura
Kenji Matsumoto
Masakazu Otsuka
Moo-Sub Kim
Shih-Kien Djeng
Hajime Monzen
Tae Suk Suh
author_facet Min-Geon Choi
Martin Law
Do-Kun Yoon
Mikoto Tamura
Kenji Matsumoto
Masakazu Otsuka
Moo-Sub Kim
Shih-Kien Djeng
Hajime Monzen
Tae Suk Suh
author_sort Min-Geon Choi
collection DOAJ
description Abstract Background An O-ring gantry-type linear accelerator (LINAC) with a 6-MV flattening filter-free (FFF) photon beam, Halcyon, includes a reference beam that contains representative information such as the percent depth dose, profile and output factor for commissioning and quality assurance. However, because it does not provide information about the field size, we proposed a method to determine all field sizes according to all depths for radiation therapy using simplified sigmoidal curve fitting (SCF). Methods After mathematical definition of the SCF using four coefficients, the defined curves were fitted to both the reference data (RD) and the measured data (MD). For good agreement between the fitting curve and the profiles in each data set, the field sizes were determined by identifying the maximum point along the third derivative of the fitting curve. The curve fitting included the field sizes for beam profiles of 2 × 2, 4 × 4, 6 × 6, 8 × 8, 10 × 10, 20 × 20 and 28 × 28 cm2 as a function of depth (at 1.3, 5, 10 and 20 cm). The field size results from the RD were compared with the results from the MD using the same condition. Results All fitting curves show goodness of fit, R2, values that are greater than 0.99. The differences in field size between the RD and the MD were within the range of 0 to 0.2 cm. The smallest difference in the field sizes at a depth of 10 cm, which is a surface-to-axis distance, was reported. Conclusion Application of the SCF method has been proven to accurately capture the field size of the preconfigured RD and the measured FFF photon beam data for the Halcyon system. The current work can be useful for beam commissioning as a countercheck methodology to determine the field size from RD in the treatment planning system of a newly installed Halcyon system and for routine quality assurance to ascertain the correctness of field sizes for clinical use of the Halcyon system.
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spelling doaj.art-d82a71fbfab44cef80f0c8d5ec6adb2a2022-12-21T22:57:17ZengBMCRadiation Oncology1748-717X2020-12-011511910.1186/s13014-020-01709-xSimplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assuranceMin-Geon Choi0Martin Law1Do-Kun Yoon2Mikoto Tamura3Kenji Matsumoto4Masakazu Otsuka5Moo-Sub Kim6Shih-Kien Djeng7Hajime Monzen8Tae Suk Suh9Department of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of KoreaProton Therapy Pte Ltd.Department of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of KoreaDepartment of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osaka-Sayama-ShiDepartment of Radiology, Kindai University Hospital, Osaka-Sayama-ShiDepartment of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osaka-Sayama-ShiDepartment of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of KoreaProton Therapy Pte Ltd.Department of Medical Physics, Graduate School of Medical Sciences, Kindai University, Osaka-Sayama-ShiDepartment of Biomedical Engineering and Research Institute of Biomedical Engineering, College of Medicine, The Catholic University of KoreaAbstract Background An O-ring gantry-type linear accelerator (LINAC) with a 6-MV flattening filter-free (FFF) photon beam, Halcyon, includes a reference beam that contains representative information such as the percent depth dose, profile and output factor for commissioning and quality assurance. However, because it does not provide information about the field size, we proposed a method to determine all field sizes according to all depths for radiation therapy using simplified sigmoidal curve fitting (SCF). Methods After mathematical definition of the SCF using four coefficients, the defined curves were fitted to both the reference data (RD) and the measured data (MD). For good agreement between the fitting curve and the profiles in each data set, the field sizes were determined by identifying the maximum point along the third derivative of the fitting curve. The curve fitting included the field sizes for beam profiles of 2 × 2, 4 × 4, 6 × 6, 8 × 8, 10 × 10, 20 × 20 and 28 × 28 cm2 as a function of depth (at 1.3, 5, 10 and 20 cm). The field size results from the RD were compared with the results from the MD using the same condition. Results All fitting curves show goodness of fit, R2, values that are greater than 0.99. The differences in field size between the RD and the MD were within the range of 0 to 0.2 cm. The smallest difference in the field sizes at a depth of 10 cm, which is a surface-to-axis distance, was reported. Conclusion Application of the SCF method has been proven to accurately capture the field size of the preconfigured RD and the measured FFF photon beam data for the Halcyon system. The current work can be useful for beam commissioning as a countercheck methodology to determine the field size from RD in the treatment planning system of a newly installed Halcyon system and for routine quality assurance to ascertain the correctness of field sizes for clinical use of the Halcyon system.https://doi.org/10.1186/s13014-020-01709-xField sizeSigmoidal curve fittingFFFHalcyonCommissioningQA
spellingShingle Min-Geon Choi
Martin Law
Do-Kun Yoon
Mikoto Tamura
Kenji Matsumoto
Masakazu Otsuka
Moo-Sub Kim
Shih-Kien Djeng
Hajime Monzen
Tae Suk Suh
Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
Radiation Oncology
Field size
Sigmoidal curve fitting
FFF
Halcyon
Commissioning
QA
title Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_full Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_fullStr Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_full_unstemmed Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_short Simplified sigmoidal curve fitting for a 6 MV FFF photon beam of the Halcyon to determine the field size for beam commissioning and quality assurance
title_sort simplified sigmoidal curve fitting for a 6 mv fff photon beam of the halcyon to determine the field size for beam commissioning and quality assurance
topic Field size
Sigmoidal curve fitting
FFF
Halcyon
Commissioning
QA
url https://doi.org/10.1186/s13014-020-01709-x
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