STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMS

In the present paper, we aimed to make two pharmaceutical forms ointment and gel, in the composition of which to be incorporated active substances with strong anti-acne and healing actions on skin lesions. The two forms, ointment and gel contain lyophilized extracts of Aloe barbandensis and Matricar...

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Main Authors: Olimpia Dumitriu Buzia, Con Madalina, Alin Laurentiu Tatu, Denisa Marin Batir, Carmen Tiutiuca, Grigore Ionuta, Gabi Topor, Sergiu Focșăneanu, Mihaela Iamandii, Ovidiu Schipor, Alina Mihaela Calin
Format: Article
Language:English
Published: Romanian Society of Oral Rehabilitation 2022-03-01
Series:Romanian Journal of Oral Rehabilitation
Subjects:
Online Access:https://www.rjor.ro/stability-and-microbiological-analysis-of-aloe-barbadensis-and-chamomilla-matricaria-pharmaceutical-forms/
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author Olimpia Dumitriu Buzia
Con Madalina
Alin Laurentiu Tatu
Denisa Marin Batir
Carmen Tiutiuca
Grigore Ionuta
Gabi Topor
Sergiu Focșăneanu
Mihaela Iamandii
Ovidiu Schipor
Alina Mihaela Calin
author_facet Olimpia Dumitriu Buzia
Con Madalina
Alin Laurentiu Tatu
Denisa Marin Batir
Carmen Tiutiuca
Grigore Ionuta
Gabi Topor
Sergiu Focșăneanu
Mihaela Iamandii
Ovidiu Schipor
Alina Mihaela Calin
author_sort Olimpia Dumitriu Buzia
collection DOAJ
description In the present paper, we aimed to make two pharmaceutical forms ointment and gel, in the composition of which to be incorporated active substances with strong anti-acne and healing actions on skin lesions. The two forms, ointment and gel contain lyophilized extracts of Aloe barbandensis and Matricaria chamomilla, in the form of alcoholic extract, as well as other active substances known, researched and used by dermatologists. We monitored the stability over time of the two pharmaceutical forms by exposure to environmental factors, and we analyzed from a microbiological point of view the behavior of the two pharmaceutical forms The study showed a strong antimicrobial action of the chemical compounds on the gram-positive germs, respectively Staphylococcus aureus, leading to the conclusion of the use of active compounds from the two plants, in alternative treatments against acne.
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spelling doaj.art-d82ebb86be53408abdbbea47669f49f72023-01-11T15:05:24ZengRomanian Society of Oral RehabilitationRomanian Journal of Oral Rehabilitation2066-70002601-46612022-03-01141216228STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMSOlimpia Dumitriu Buzia0Con Madalina1Alin Laurentiu Tatu2Denisa Marin Batir3Carmen Tiutiuca4Grigore Ionuta5Gabi Topor6Sergiu Focșăneanu7Mihaela Iamandii8Ovidiu SchiporAlina Mihaela Calin9Dunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaCollege of Pharmacists, 27 Galati Str., 810388, Galati, Romania Dunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaDunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaDunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaDunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaDunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaDunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaDunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaDunarea de Jos University, Faculty of Medicine and Pharmacy,35 Al. I. Cuza Str., 800010, Galati, RomaniaIn the present paper, we aimed to make two pharmaceutical forms ointment and gel, in the composition of which to be incorporated active substances with strong anti-acne and healing actions on skin lesions. The two forms, ointment and gel contain lyophilized extracts of Aloe barbandensis and Matricaria chamomilla, in the form of alcoholic extract, as well as other active substances known, researched and used by dermatologists. We monitored the stability over time of the two pharmaceutical forms by exposure to environmental factors, and we analyzed from a microbiological point of view the behavior of the two pharmaceutical forms The study showed a strong antimicrobial action of the chemical compounds on the gram-positive germs, respectively Staphylococcus aureus, leading to the conclusion of the use of active compounds from the two plants, in alternative treatments against acne.https://www.rjor.ro/stability-and-microbiological-analysis-of-aloe-barbadensis-and-chamomilla-matricaria-pharmaceutical-forms/chamomile. aloe veraointmentgelacne
spellingShingle Olimpia Dumitriu Buzia
Con Madalina
Alin Laurentiu Tatu
Denisa Marin Batir
Carmen Tiutiuca
Grigore Ionuta
Gabi Topor
Sergiu Focșăneanu
Mihaela Iamandii
Ovidiu Schipor
Alina Mihaela Calin
STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMS
Romanian Journal of Oral Rehabilitation
chamomile. aloe vera
ointment
gel
acne
title STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMS
title_full STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMS
title_fullStr STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMS
title_full_unstemmed STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMS
title_short STABILITY AND MICROBIOLOGICAL ANALYSIS OF ALOE BARBADENSIS AND CHAMOMILLA MATRICARIA PHARMACEUTICAL FORMS
title_sort stability and microbiological analysis of aloe barbadensis and chamomilla matricaria pharmaceutical forms
topic chamomile. aloe vera
ointment
gel
acne
url https://www.rjor.ro/stability-and-microbiological-analysis-of-aloe-barbadensis-and-chamomilla-matricaria-pharmaceutical-forms/
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