Glutamate Receptor GRIA3—Target of CUX1 and Mediator of Tumor Progression in Pancreatic Cancer

Glutamate Receptor GRIA3—Target of CUX1 and Mediator of Tumor Progression in Pancreatic Cancer

Previously, we identified the transcription factor CUX1 as an important modulator of invasion and resistance to apoptosis. Expression profiles suggested that CUX1 regulates a complex transcriptional program mediating tumor progression. We aimed to identify functionally relevant targets of CUX1 by us...

Full description

Bibliographic Details
Main Authors:	Stefanie Ripka, Jan Riedel, Albrecht Neesse, Heidi Griesmann, Malte Buchholz, Volker Ellenrieder, Franz Moeller, Peter Bartht, Thomas M. Gress, Patrick Michl
Format:	Article
Language:	English
Published:	Elsevier 2010-08-01
Series:	Neoplasia: An International Journal for Oncology Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1476558610800673

Similar Items

WNT5A-NFAT Signaling Mediates Resistance to Apoptosis in Pancreatic Cancer
by: Heidi Griesmann, et al.
Published: (2013-01-01)

Screening Technologies for Target Identification in Pancreatic Cancer
by: Thomas Gress, et al.
Published: (2010-12-01)

CUX1 Enhances Pancreatic Cancer Formation by Synergizing with KRAS and Inducing MEK/ERK-Dependent Proliferation
by: Heidi Griesmann, et al.
Published: (2021-05-01)

Synthetic Lethality Screen Identifies RPS6KA2 as Modifier of Epidermal Growth Factor Receptor Activity in Pancreatic Cancer
by: Nada Milosevic, et al.
Published: (2013-12-01)

CUX1—Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors
by: Sebastian Krug, et al.
Published: (2020-07-01)

Simultaneous Onset of Ulcerative Colitis and Disseminated Pyoderma Gangrenosum
by: Albrecht Neesse, et al.
Published: (2007-10-01)

873 Pharmacologic macrophage depletion affects metastasis formation by modulating systemic immune responses in a genetic pancreatic cancer model
by: Patrick Michl, et al.
Published: (2020-11-01)

Stromal Features of the Primary Tumor Are Not Prognostic in Genetically Engineered Mice of Pancreatic Cancer
by: Marie C. Hasselluhn, et al.
Published: (2019-12-01)

Common variants in the regulative regions of <it>GRIA1 </it>and <it>GRIA3 </it>receptor genes are associated with migraine susceptibility
by: Gianfrancesco Fernando, et al.
Published: (2010-06-01)

Author index
by: Patrick Michl, et al.
Published: (2020-11-01)

Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer
by: Soeren M. Buchholz, et al.
Published: (2020-07-01)

Preclinical Evaluation of 1,2-Diamino-4,5-Dibromobenzene in Genetically Engineered Mouse Models of Pancreatic Cancer
by: Robert G. Goetze, et al.
Published: (2019-06-01)

Experiences with GRIA - Industrial Applications on a Web Services Grid.
by: Surridge, M, et al.
Published: (2005)

Unraveling genetic modifiers in the gria4 mouse model of absence epilepsy.
by: Wayne N Frankel, et al.
Published: (2014-07-01)

Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer
by: Shilpa Patil, et al.
Published: (2021-12-01)

Metabolomics-based alleviation of depression by Xiaoyaosan through regulation of XDH and GRIA2
by: Chaofang Lei, et al.
Published: (2023-09-01)

IGF2BP1 Promotes Proliferation of Neuroendocrine Neoplasms by Post-Transcriptional Enhancement of EZH2
by: Florian Sperling, et al.
Published: (2022-04-01)

Gall bladder wall thickening as non-invasive screening parameter for esophageal varices – a comparative endoscopic – sonographic study
by: Birgit Tsaknakis, et al.
Published: (2018-08-01)

Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells.
by: Alexander Hann, et al.
Published: (2011-01-01)

Epithelial-Mesenchymal Transition Is a Critical Step in Tumorgenesis of Pancreatic Neuroendocrine Tumors
by: Alexander König, et al.
Published: (2012-03-01)

CUX1 in leukemia: dosage matters.
by: Boultwood, J
Published: (2013)

Cerebellar glutamatergic system impacts spontaneous motor recovery by regulating Gria1 expression
by: Pallavi Asthana, et al.
Published: (2022-09-01)

Attenuation of Novelty-Induced Hyperactivity of Gria1-/- Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics
by: Teemu Aitta-aho, et al.
Published: (2019-03-01)

<i>TP53</i>-Status-Dependent Oncogenic EZH2 Activity in Pancreatic Cancer
by: Lennart Versemann, et al.
Published: (2022-07-01)

Magnetotransport CuxBi2Se3
by: Coldea, A, et al.
Published: (2018)

GRIA3 p.Met661Thr variant in a female with developmental epileptic encephalopathy
by: Satomi Okano, et al.
Published: (2023-02-01)

Tunnelled Peritoneal Catheter for Malignant Ascites—An Open-Label, Prospective, Observational Trial
by: Golo Petzold, et al.
Published: (2021-06-01)

P268: A functionally uncharacterized, novel GRIA2 variant: Advances in targeted epilepsy management
by: Reilly Philliben
Published: (2023-01-01)

Synthesis of CuxS/Cu nanotubes and their lithium storage properties
by: Cai, Ren, et al.
Published: (2013)

Formation of CuxS Layers on Polypropylene Sulfurized by Molten Sulfur
by: Rasa ALABURDAITĖ, et al.
Published: (2011-11-01)

CUX1, A Controversial Player in Tumor Development
by: Ning Liu, et al.
Published: (2020-05-01)

Density and Surface Tension of CuxO Bearing Slags
by: Takasu, T., et al.
Published: (2003-08-01)

Thermodynamic stability of CuxAg1-x nanoparticles
by: I.V. Chepkasov, et al.
Published: (2017-12-01)

Electronic Metal-Support Interactions Between CuxO and ZnO for CuxO/ZnO Catalysts With Enhanced CO Oxidation Activity
by: Shuai Lyu, et al.
Published: (2022-05-01)

A multistep high-content screening approach to identify novel functionally relevant target genes in pancreatic cancer.
by: Malte Buchholz, et al.
Published: (2015-01-01)

IL18 Receptor Signaling Inhibits Intratumoral CD8<sup>+</sup> T-Cell Migration in a Murine Pancreatic Cancer Model
by: Elena Nasiri, et al.
Published: (2023-01-01)

Comparison of Chest Ultrasound and Standard X-Ray Imaging in COVID-19 Patients
by: Evgenii Shumilov, et al.
Published: (2020-09-01)

Urokinase-Type Plasminogen Activator Receptor (uPAR) Cooperates with Mutated <i>KRAS</i> in Regulating Cellular Plasticity and Gemcitabine Response in Pancreatic Adenocarcinomas
by: Luogen Peng, et al.
Published: (2023-03-01)

Novel Heterozygous Missense Variant in GRIA4 Gene Associated With Neurodevelopmental Disorder With or Without Seizures and Gait Abnormalities
by: Hua Wang, et al.
Published: (2022-04-01)

Islam dan Pengobatan Abad 21: Balur Gria Muria Kudus Pengobatan Kolaborasi Ilmuwan dan Tabib
by: Sayyidah Aslamah
Published: (2018-12-01)