Pediatric Bone Marrow Failure: A Broad Landscape in Need of Personalized Management

Pediatric Bone Marrow Failure: A Broad Landscape in Need of Personalized Management

Irreversible severe bone marrow failure (BMF) is a life-threatening condition in pediatric patients. Most important causes are inherited bone marrow failure syndromes (IBMFSs) and (pre)malignant diseases, such as myelodysplastic syndrome (MDS) and (idiopathic) aplastic anemia (AA). Timely treatment...

Full description

Bibliographic Details
Main Authors:	Lotte T. W. Vissers, Mirjam van der Burg, Arjan C. Lankester, Frans J. W. Smiers, Marije Bartels, Alexander B. Mohseny
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Journal of Clinical Medicine
Subjects:	cytopenia aplastic anemia bone marrow failure myelodysplastic syndrome hematopoietic stem cell transplantation immunosuppressive therapy
Online Access:	https://www.mdpi.com/2077-0383/12/22/7185

Similar Items

Diagnostic Value of a Protocolized In-Depth Evaluation of Pediatric Bone Marrow Failure: A Multi-Center Prospective Cohort Study
by: Khaled Atmar, et al.
Published: (2022-04-01)

Aplastic Anemia as a Roadmap for Bone Marrow Failure: An Overview and a Clinical Workflow
by: Antonio G. Solimando, et al.
Published: (2022-10-01)

Functional and Immune Modulatory Characteristics of Bone Marrow Mesenchymal Stromal Cells in Patients With Aplastic Anemia: A Systematic Review
by: Khaled Atmar, et al.
Published: (2022-03-01)

Bone marrow transplantation/non-bone marrow transplantation gap: to what extent does it exist in the Egyptian children with acquired aplastic anemia? Retrospective descriptive study
by: Mohamed Abdallah Abd El Megied, et al.
Published: (2023-10-01)

Bone Marrow Failure Syndromes, Overlapping Diseases with a Common Cytokine Signature
by: Valentina Giudice, et al.
Published: (2021-01-01)

Research advance on telomere shortening and bone marrow failure diseases
by: GAO Xiao-yan, LIU Shu-chuan
Published: (2021-01-01)

Irisin protected hemopoietic stem cells and improved outcome of severe bone marrow failure
by: Hui Li, et al.
Published: (2023-12-01)

Immunoexpression of CD34, CD117, and p53 in Hypocellular Bone Marrow Disorders
by: Pooja Sharma, et al.
Published: (2022-06-01)

Mesenchymal Stem Cells in Aplastic Anemia and Myelodysplastic Syndromes: The “Seed and Soil” Crosstalk
by: Bruno Fattizzo, et al.
Published: (2020-07-01)

Missing cells: pathophysiology, diagnosis and management of (pan)cytopenia in childhood
by: Miriam eErlacher, et al.
Published: (2015-07-01)

The use of allogeneic bone marrow transplantation and immunosuppressive therapy in the treatment of patients with acquired aplastic anemia
by: A A Ganapiyev, et al.
Published: (2010-07-01)

Identification of Plasma Thrombopoietin Level and Its Significance in Patients with Aplastic Anemia and Myelodysplastic Syndrome
by: Mengying Zhang, et al.
Published: (2023-09-01)

Comparison of bone marrow aspiration cytology with bone marrow trephine biopsy histopathology: An observational study
by: Meenu Gilotra, et al.
Published: (2017-07-01)

Hypercellular bone marrow in aplastic anemia: A case report of two patients
by: Ryan Sweeney, et al.
Published: (2021-11-01)

SPECTRUM OF HEMATOLOGICAL DISEASES IN CHILDREN PRESENTING WITH ANEMIA BASED ON BONE MARROW EXAMINATION
by: Zahid Gul, et al.
Published: (2014-09-01)

Current management of severe acquired aplastic anemia
by: Phillip Scheinberg
Published: (2011-06-01)

Síndromes mielodisplásicas: protocolo de exclusão Myelodysplastic syndrome: diagnostic protocol
by: Silvia Maria M. Magalhães, et al.
Published: (2004-12-01)

Hypoplastic Myelodysplastic Syndromes: Just an Overlap Syndrome?
by: Bruno Fattizzo, et al.
Published: (2021-01-01)

Bone marrow findings in rheumatoid arthritis patients with peripheral cytopenias
by: Mohamed A Abd El Hafez, et al.
Published: (2019-01-01)

Bone Marrow Fat and Hematopoiesis
by: Huifang Wang, et al.
Published: (2018-11-01)

When Should We Think of Myelodysplasia or Bone Marrow Failure in a Thrombocytopenic Patient? A Practical Approach to Diagnosis
by: Nicolas Bonadies, et al.
Published: (2021-03-01)

Aplasia medular: Actualización Bone marrow aplasia: Update
by: Sergio Machín García, et al.
Published: (1999-08-01)

The state of the art in the treatment of severe aplastic anemia: immunotherapy and hematopoietic cell transplantation in children and adults
by: Agnieszka Piekarska, et al.
Published: (2024-04-01)

Efficacy of eltrombopag with immunosuppressive therapy for children with acquired aplastic anemia
by: Yufei Zhao, et al.
Published: (2023-01-01)

False Negativity of Tc-99m Labeled Sodium Phytate Bone Marrow Imaging Under the Effect of G-CSF Prescription in Aplastic Anemia: A Case Report
by: Akanganyira Kasenene, et al.
Published: (2019-01-01)

Anti Thymocyte Globulin-Based Treatment for Acquired Bone Marrow Failure in Adults
by: Jennifer M.-L. Tjon, et al.
Published: (2021-10-01)

A Deep Learning Model for the Automatic Recognition of Aplastic Anemia, Myelodysplastic Syndromes, and Acute Myeloid Leukemia Based on Bone Marrow Smear
by: Meifang Wang, et al.
Published: (2022-04-01)

APLASTIC ANEMIA AND HEALTH OF THE ORAL CAVITY- CLINICAL CONSIDERATIONS
by: Cristina Claudia Tărniceriu, et al.
Published: (2022-03-01)

Immunosuppressive Treatment in Children with Acquired Aplastic Anemia
by: Yıldız Yıldırmak, et al.
Published: (2012-05-01)

Idiopathic Aplastic Anemia: An Update
by: Elena E. Solomou
Published: (2019-03-01)

Mass cytometric analysis unveils a disease-specific immune cell network in the bone marrow in acquired aplastic anemia
by: Emma S. Pool, et al.
Published: (2023-11-01)

Comparisons Between Frontline Therapy and a Combination of Eltrombopag Plus Immunosuppression Therapy and Human Leukocyte Antigen-Haploidentical Hematopoietic Stem Cell Transplantation in Patients With Severe Aplastic Anemia: A Systematic Review
by: Yuan Yang, et al.
Published: (2021-04-01)

Large Granular Lymphocyte Expansion in Myeloid Diseases and Bone Marrow Failure Syndromes: Whoever Seeks Finds
by: Bruno Fattizzo, et al.
Published: (2021-10-01)

Clinical, Morphological and Clonal Progression of VEXAS Syndrome in the Context of Myelodysplasia Treated with Azacytidine
by: Marco Manzoni, et al.
Published: (2022-05-01)

Plasma proteome changes associated with refractory cytopenia with multilineage dysplasia
by: Čermák Jaroslav, et al.
Published: (2011-10-01)

Azathioprine-Induced Severe Bone Marrow Suppression
by: Marzie Ghalamkari, et al.
Published: (2019-07-01)

Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
by: Maria Stella Figueiredo, et al.

Hemophagocytosis in bone marrow aspirates: An indication of hidden pathologies
by: Sampath Kolavadi Srinivasagowda, et al.
Published: (2019-01-01)

Fatal Hepatitis-Associated Aplastic Anemia in a Young Male
by: Dorotea Božić Ozretić, et al.
Published: (2020-07-01)

Bone marrow involvement in sarcoidosis: an elusive extrapulmonary manifestation
by: J. Isaac Peña-Garcia, et al.
Published: (2019-03-01)