The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines
The present study was carried out to evaluate the cytological effects of aqueous (AE) and ethanolic (EE) extracts of Artemisia herba alba on human laryngeal carcinoma (Hep-2) cell line and murine mammary adenocarcinoma (AMN-3) cell line in vitro. The cytological study performed simultaneously with...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mirror of Research in Veterinary Sciences and Animals (MRVSA)
2016-07-01
|
| Series: | Mirror of Research in Veterinary Sciences and Animals |
| Subjects: | |
| Online Access: | http://mrvsa.com/upload/article%202%20The%20effect%20of%20aqueous%20and%20ethanolic%20extracts%20of%20Artemisia%20herba.pdf |
| _version_ | 1818645779966853120 |
|---|---|
| author | Khalil H. Al- Jeboori Ahmed H. Al- Dabhawi Nahi Y. Yaseen |
| author_facet | Khalil H. Al- Jeboori Ahmed H. Al- Dabhawi Nahi Y. Yaseen |
| author_sort | Khalil H. Al- Jeboori |
| collection | DOAJ |
| description | The present study was carried out to evaluate the cytological effects of aqueous
(AE) and ethanolic (EE) extracts of Artemisia herba alba on human laryngeal carcinoma (Hep-2) cell line and murine mammary adenocarcinoma (AMN-3) cell line in vitro. The cytological study performed simultaneously with cell growth assay. The results of study revealed concentration-dependent cytological changes like patchy growth inhibition, loss of confluent feature and cellular degeneration after exposure to the lowest concentrations (156.25 and 312.5 μg/ml). The early findings of cytolysis were seen after exposure to 625 μg/ml. While the highest concentrations (1250, 2500 and 5000 μg/ml) caused severe growth inhibition with marked cytolytic features including loss of cellular
outlines, large numbers of dead cells and high content of cellular debris. In conclusion, the results of this study revealed the high cytological effect of Artemisia herba alba extracts on Hep-2 and AMN-3 cell lines in vitro. |
| first_indexed | 2024-12-17T00:36:10Z |
| format | Article |
| id | doaj.art-d83d248723a94a77bf5b32b30fd4c3bb |
| institution | Directory Open Access Journal |
| issn | 2520-324X 2520-324X |
| language | English |
| last_indexed | 2024-12-17T00:36:10Z |
| publishDate | 2016-07-01 |
| publisher | Mirror of Research in Veterinary Sciences and Animals (MRVSA) |
| record_format | Article |
| series | Mirror of Research in Veterinary Sciences and Animals |
| spelling | doaj.art-d83d248723a94a77bf5b32b30fd4c3bb2022-12-21T22:10:08ZengMirror of Research in Veterinary Sciences and Animals (MRVSA)Mirror of Research in Veterinary Sciences and Animals2520-324X2520-324X2016-07-01521119The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell linesKhalil H. Al- Jeboori0Ahmed H. Al- Dabhawi1Nahi Y. Yaseen2Department of pathology/ College of Veterinary Medicine / University of Baghdad/IraqDepartment of pathology/ College of Veterinary Medicine / University of Kufa /IraqIraqi center for cancer and cytogenetic research / University of Al Munstansiriya / IraqThe present study was carried out to evaluate the cytological effects of aqueous (AE) and ethanolic (EE) extracts of Artemisia herba alba on human laryngeal carcinoma (Hep-2) cell line and murine mammary adenocarcinoma (AMN-3) cell line in vitro. The cytological study performed simultaneously with cell growth assay. The results of study revealed concentration-dependent cytological changes like patchy growth inhibition, loss of confluent feature and cellular degeneration after exposure to the lowest concentrations (156.25 and 312.5 μg/ml). The early findings of cytolysis were seen after exposure to 625 μg/ml. While the highest concentrations (1250, 2500 and 5000 μg/ml) caused severe growth inhibition with marked cytolytic features including loss of cellular outlines, large numbers of dead cells and high content of cellular debris. In conclusion, the results of this study revealed the high cytological effect of Artemisia herba alba extracts on Hep-2 and AMN-3 cell lines in vitro.http://mrvsa.com/upload/article%202%20The%20effect%20of%20aqueous%20and%20ethanolic%20extracts%20of%20Artemisia%20herba.pdfArtemisia herba albaaqueous extractcytological effectscell linesin vitro. |
| spellingShingle | Khalil H. Al- Jeboori Ahmed H. Al- Dabhawi Nahi Y. Yaseen The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines Mirror of Research in Veterinary Sciences and Animals Artemisia herba alba aqueous extract cytological effects cell lines in vitro. |
| title | The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines |
| title_full | The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines |
| title_fullStr | The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines |
| title_full_unstemmed | The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines |
| title_short | The effect of aqueous and ethanolic extracts of Artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines |
| title_sort | effect of aqueous and ethanolic extracts of artemisia herba alba on human laryngeal carcinoma and murine mammary adenocarcinoma cell lines |
| topic | Artemisia herba alba aqueous extract cytological effects cell lines in vitro. |
| url | http://mrvsa.com/upload/article%202%20The%20effect%20of%20aqueous%20and%20ethanolic%20extracts%20of%20Artemisia%20herba.pdf |
| work_keys_str_mv | AT khalilhaljeboori theeffectofaqueousandethanolicextractsofartemisiaherbaalbaonhumanlaryngealcarcinomaandmurinemammaryadenocarcinomacelllines AT ahmedhaldabhawi theeffectofaqueousandethanolicextractsofartemisiaherbaalbaonhumanlaryngealcarcinomaandmurinemammaryadenocarcinomacelllines AT nahiyyaseen theeffectofaqueousandethanolicextractsofartemisiaherbaalbaonhumanlaryngealcarcinomaandmurinemammaryadenocarcinomacelllines AT khalilhaljeboori effectofaqueousandethanolicextractsofartemisiaherbaalbaonhumanlaryngealcarcinomaandmurinemammaryadenocarcinomacelllines AT ahmedhaldabhawi effectofaqueousandethanolicextractsofartemisiaherbaalbaonhumanlaryngealcarcinomaandmurinemammaryadenocarcinomacelllines AT nahiyyaseen effectofaqueousandethanolicextractsofartemisiaherbaalbaonhumanlaryngealcarcinomaandmurinemammaryadenocarcinomacelllines |