Use of fludrocortisone for intradialytic hypotension

Intradialytic hypotension during dialysis adversely affects a patient's prognosis and increases mortality. We report a case in which intradialytic hypotension that persisted after the administration of midodrine was relieved after the use of fludrocortisone. Administration of 0.2 mg of fludroco...

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Main Authors: Yuri Seo, Soomin Jeung, Sun-myoung Kang, Won Seok Yang, Hyosang Kim, Soon Bae Kim
Format: Article
Language:English
Published: The Korean Society of Nephrology 2018-03-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:https://doi.org/10.23876/j.krcp.2018.37.1.85
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author Yuri Seo
Soomin Jeung
Sun-myoung Kang
Won Seok Yang
Hyosang Kim
Soon Bae Kim
author_facet Yuri Seo
Soomin Jeung
Sun-myoung Kang
Won Seok Yang
Hyosang Kim
Soon Bae Kim
author_sort Yuri Seo
collection DOAJ
description Intradialytic hypotension during dialysis adversely affects a patient's prognosis and increases mortality. We report a case in which intradialytic hypotension that persisted after the administration of midodrine was relieved after the use of fludrocortisone. Administration of 0.2 mg of fludrocortisone occurred 30 minutes before dialysis. We compared 45 sessions of dialysis without fludrocortisone administration and 45 sessions of dialysis with fludrocortisone administration in one patient. The number of times in which systolic blood pressure became lower than 80 mmHg and the number of early terminations of dialysis due to a decrease in systolic blood pressure were higher in the sessions without fludrocortisone administration than in the sessions with fludrocortisone administration (P < 0.05). Fludrocortisone may be helpful for the treatment of intradialytic hypotension that does not respond to midodrine administration.
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spelling doaj.art-d84942db46804de8af6c802fa3bdc2582022-12-21T17:43:12ZengThe Korean Society of NephrologyKidney Research and Clinical Practice2211-91322018-03-01371858810.23876/j.krcp.2018.37.1.85j.krcp.2018.37.1.85Use of fludrocortisone for intradialytic hypotensionYuri Seo0Soomin Jeung1Sun-myoung Kang2Won Seok Yang3Hyosang Kim4Soon Bae Kim5Department of Nephrology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaDepartment of Nephrology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaDepartment of Nephrology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaDepartment of Nephrology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaDepartment of Nephrology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaDepartment of Nephrology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaIntradialytic hypotension during dialysis adversely affects a patient's prognosis and increases mortality. We report a case in which intradialytic hypotension that persisted after the administration of midodrine was relieved after the use of fludrocortisone. Administration of 0.2 mg of fludrocortisone occurred 30 minutes before dialysis. We compared 45 sessions of dialysis without fludrocortisone administration and 45 sessions of dialysis with fludrocortisone administration in one patient. The number of times in which systolic blood pressure became lower than 80 mmHg and the number of early terminations of dialysis due to a decrease in systolic blood pressure were higher in the sessions without fludrocortisone administration than in the sessions with fludrocortisone administration (P < 0.05). Fludrocortisone may be helpful for the treatment of intradialytic hypotension that does not respond to midodrine administration.https://doi.org/10.23876/j.krcp.2018.37.1.85FludrocortisoneHypotensionMidodrineRenal dialysis
spellingShingle Yuri Seo
Soomin Jeung
Sun-myoung Kang
Won Seok Yang
Hyosang Kim
Soon Bae Kim
Use of fludrocortisone for intradialytic hypotension
Kidney Research and Clinical Practice
Fludrocortisone
Hypotension
Midodrine
Renal dialysis
title Use of fludrocortisone for intradialytic hypotension
title_full Use of fludrocortisone for intradialytic hypotension
title_fullStr Use of fludrocortisone for intradialytic hypotension
title_full_unstemmed Use of fludrocortisone for intradialytic hypotension
title_short Use of fludrocortisone for intradialytic hypotension
title_sort use of fludrocortisone for intradialytic hypotension
topic Fludrocortisone
Hypotension
Midodrine
Renal dialysis
url https://doi.org/10.23876/j.krcp.2018.37.1.85
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