Efficient allelic-drive in Drosophila

Efficient allelic-drive in Drosophila

Gene-drives use CRISPR-Cas9 to be transmitted in a super-Mendelian fashion. Here the authors develop an allelic-drive for selective inheritance of a desired allele.

Bibliographic Details
Main Authors:	Annabel Guichard, Tisha Haque, Marketta Bobik, Xiang-Ru S. Xu, Carissa Klanseck, Raja Babu Singh Kushwah, Mateus Berni, Bhagyashree Kaduskar, Valentino M. Gantz, Ethan Bier
Format:	Article
Language:	English
Published:	Nature Portfolio 2019-04-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-09694-w

Similar Items

Reversing insecticide resistance with allelic-drive in Drosophila melanogaster
by: Bhagyashree Kaduskar, et al.
Published: (2022-01-01)

Deconstructing host-pathogen interactions in Drosophila
by: Ethan Bier, et al.
Published: (2012-01-01)

CRISPR/Cas9 and active genetics-based trans-species replacement of the endogenous Drosophila kni-L2 CRM reveals unexpected complexity
by: Xiang-Ru Shannon Xu, et al.
Published: (2017-12-01)

tgCRISPRi: efficient gene knock-down using truncated gRNAs and catalytically active Cas9
by: Ankush Auradkar, et al.
Published: (2023-09-01)

Author Correction: tgCRISPRi: efficient gene knock-down using truncated gRNAs and catalytically active Cas9
by: Ankush Auradkar, et al.
Published: (2024-04-01)

A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways
by: Ruth Schwartz, et al.
Published: (2020-02-01)

Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes
by: Nikolay P. Kandul, et al.
Published: (2020-02-01)

Double-tap gene drive uses iterative genome targeting to help overcome resistance alleles
by: Alena L. Bishop, et al.
Published: (2022-05-01)

Inherently confinable split-drive systems in Drosophila
by: Gerard Terradas, et al.
Published: (2021-03-01)

CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
by: Zhiqian Li, et al.
Published: (2021-05-01)

Developmental progression of DNA double-strand break repair deciphered by a single-allele resolution mutation classifier
by: Zhiqian Li, et al.
Published: (2024-03-01)

SUMO conjugation regulates immune signalling
by: Sushmitha Hegde, et al.
Published: (2020-10-01)

Regulation of Drosophila Lifespan by bellwether Promoter Alleles
by: Júlia Frankenberg Garcia, et al.
Published: (2017-06-01)

A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
by: Víctor López Del Amo, et al.
Published: (2020-01-01)

Neural basis of hunger-driven behaviour in Drosophila
by: Suewei Lin, et al.
Published: (2019-03-01)

Fine mapping of dominant X-linked incompatibility alleles in Drosophila hybrids.
by: Daniel R Matute, et al.
Published: (2014-04-01)

Retraction: Functional conservation of the Drosophila gooseberry gene and its evolutionary alleles.
Published: (2012-01-01)

Allele frequency divergence reveals ubiquitous influence of positive selection in Drosophila.
by: Jason Bertram
Published: (2021-09-01)

Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline.
by: Alexander J Weitzel, et al.
Published: (2021-12-01)

Involvement of an SCF<sup>Slmb</sup> complex in timely elimination of E2F upon initiation of DNA replication in <it>Drosophila</it>
by: O'Farrell Patrick H, et al.
Published: (2003-06-01)

A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins
by: Annabel Guichard, et al.
Published: (2023-08-01)

Correction: Characterization of a cdc14 null allele in Drosophila melanogaster (doi:10.1242/bio.035394)
by: Leif Neitzel, et al.
Published: (2018-08-01)

BMPs regulate msx gene expression in the dorsal neuroectoderm of Drosophila and vertebrates by distinct mechanisms.
by: Francisco F Esteves, et al.
Published: (2014-09-01)

Tools and strategies for scarless allele replacement in Drosophila using CRISPR/Cas9
by: Abigail M. Lamb, et al.
Published: (2017-01-01)

Correction: Fine Mapping of Dominant X-Linked Incompatibility Alleles in Drosophila Hybrids.
by: Daniel R Matute, et al.
Published: (2015-10-01)

Generation of CG3509 mutant allele(s) by p-element excision in Drosophila melanogaster.
by: Wong, Joyner Yin Sze.
Published: (2012)

Generation of New Hairless Alleles by Genomic Engineering at the Hairless Locus in Drosophila melanogaster.
by: Heiko Praxenthaler, et al.
Published: (2015-01-01)

Sensitivity of Allelic Divergence to Genomic Position: Lessons from the Drosophila tan Gene
by: Alisha V. John, et al.
Published: (2016-09-01)

Author Correction: Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
by: Mahul Chakraborty, et al.
Published: (2022-05-01)

Polymorphisms of inversions and <it>Adh </it>alleles in eye colour mutant experimental populations of <it>Drosophila melanogaster</it>
by: Ménsua JL, et al.
Published: (1987-09-01)

Natural alleles of the clock gene timeless differentially affect life-history traits in Drosophila
by: Gabriele Andreatta, et al.
Published: (2023-01-01)

Shared Transcriptional Machinery at Homologous Alleles Leads to Reduced Transcription in Early Drosophila Embryos
by: Hao Deng, et al.
Published: (2022-07-01)

Genetic dissection of the Drosophila melanogaster female head transcriptome reveals widespread allelic heterogeneity.
by: Elizabeth G King, et al.
Published: (2014-05-01)

Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi
by: Adriana Adolfi, et al.
Published: (2020-11-01)

Isolation of AMP-activated protein kinase (AMPK) alleles required for neuronal maintenance in Drosophila melanogaster
by: Lance L. Swick, et al.
Published: (2013-10-01)

Somatic clones heterozygous for recessive disease alleles of BMPR1A exhibit unexpected phenotypes in Drosophila
by: Takuya Akiyama, et al.
Published: (2018-05-01)

An attempt to modify allelic frequencies at the <it>Adh </it>locus of a <it>Drosophila melanogaster </it>population in a tropical environment
by: David JR
Published: (1983-10-01)

Adaptation of Drosophila larva foraging in response to changes in food resources
by: Marina E Wosniack, et al.
Published: (2022-12-01)

An asymmetric allelic interaction drives allele transmission bias in interspecific rice hybrids
by: Yongyao Xie, et al.
Published: (2019-06-01)

Biosimilar insulins: An unavoidable option in South-East Asia
by: Prashant Ulhas Kaduskar
Published: (2016-01-01)