The study of the Profort probiotic use in the specific prevention of salmonellosis in calves
In order to increase the post-vaccination immune response during vaccination of calves against salmonellosis, a test was carried out with an inactivated emulsified vaccine against the background of the use of the probiotic Profort. The studies were carried out on the basis of a large livestock farm...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2022-01-01
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| Series: | E3S Web of Conferences |
| Online Access: | https://www.e3s-conferences.org/articles/e3sconf/pdf/2022/30/e3sconf_interagromash2022_03064.pdf |
| _version_ | 1797951192996773888 |
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| author | Manzhurina Olga Shaposhnikov Ivan Yermakova Tatyana Bliznetsova Galina Parkhomenko Yulia Kotarev Vyacheslav Bryukhova Irina |
| author_facet | Manzhurina Olga Shaposhnikov Ivan Yermakova Tatyana Bliznetsova Galina Parkhomenko Yulia Kotarev Vyacheslav Bryukhova Irina |
| author_sort | Manzhurina Olga |
| collection | DOAJ |
| description | In order to increase the post-vaccination immune response during vaccination of calves against salmonellosis, a test was carried out with an inactivated emulsified vaccine against the background of the use of the probiotic Profort. The studies were carried out on the basis of a large livestock farm in the Voronezh region, unfavorable for salmonellosis of calves. Epizootological, clinical, immunological, hematological, molecular genetic research methods were used in the work. Studies have shown that vaccination of calves against salmonellosis against the background of the use of the probiotic preparation Profort with an inactivated emulsified vaccine contributed to the development of intense cellular immunity – an increase in the total number of lymphocytes and T-cells by 7.0%, B-cells – by 2.8%%, phagocytic activity of neutrophils - by 5.9%, phagocytic number – by 7.2%, phagocytic index – by 7.0%, as well as humoral immunity factors – BaS by 3.0%, LaS – by 3.0%%, CaS – by 1.7%, O- and H-agglutinins to salmonella antigen – 1.5 and 2 times, respectively. The use of Profort increases the protective properties of the vaccine against salmonellosis, helps to reduce the incidence by 13.3%, and increase the safety of young animals by 26.6%. Therefore, to optimize the use of Profort probiotic, it is necessary to take into account its immunomodulatory effect. |
| first_indexed | 2024-04-10T22:26:45Z |
| format | Article |
| id | doaj.art-d84cb89b621a4861a80fdc93d1e691fa |
| institution | Directory Open Access Journal |
| issn | 2267-1242 |
| language | English |
| last_indexed | 2024-04-10T22:26:45Z |
| publishDate | 2022-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | E3S Web of Conferences |
| spelling | doaj.art-d84cb89b621a4861a80fdc93d1e691fa2023-01-17T09:12:04ZengEDP SciencesE3S Web of Conferences2267-12422022-01-013630306410.1051/e3sconf/202236303064e3sconf_interagromash2022_03064The study of the Profort probiotic use in the specific prevention of salmonellosis in calvesManzhurina Olga0Shaposhnikov Ivan1Yermakova Tatyana2Bliznetsova Galina3Parkhomenko Yulia4Kotarev Vyacheslav5Bryukhova Irina6All-Russian Research Veterinary Institute of Pathology, Pharmacology and TherapyAll-Russian Research Veterinary Institute of Pathology, Pharmacology and TherapyAll-Russian Research Veterinary Institute of Pathology, Pharmacology and TherapyAll-Russian Research Veterinary Institute of Pathology, Pharmacology and TherapyAll-Russian Research Veterinary Institute of Pathology, Pharmacology and TherapyAll-Russian Research Veterinary Institute of Pathology, Pharmacology and TherapyAll-Russian Research Veterinary Institute of Pathology, Pharmacology and TherapyIn order to increase the post-vaccination immune response during vaccination of calves against salmonellosis, a test was carried out with an inactivated emulsified vaccine against the background of the use of the probiotic Profort. The studies were carried out on the basis of a large livestock farm in the Voronezh region, unfavorable for salmonellosis of calves. Epizootological, clinical, immunological, hematological, molecular genetic research methods were used in the work. Studies have shown that vaccination of calves against salmonellosis against the background of the use of the probiotic preparation Profort with an inactivated emulsified vaccine contributed to the development of intense cellular immunity – an increase in the total number of lymphocytes and T-cells by 7.0%, B-cells – by 2.8%%, phagocytic activity of neutrophils - by 5.9%, phagocytic number – by 7.2%, phagocytic index – by 7.0%, as well as humoral immunity factors – BaS by 3.0%, LaS – by 3.0%%, CaS – by 1.7%, O- and H-agglutinins to salmonella antigen – 1.5 and 2 times, respectively. The use of Profort increases the protective properties of the vaccine against salmonellosis, helps to reduce the incidence by 13.3%, and increase the safety of young animals by 26.6%. Therefore, to optimize the use of Profort probiotic, it is necessary to take into account its immunomodulatory effect.https://www.e3s-conferences.org/articles/e3sconf/pdf/2022/30/e3sconf_interagromash2022_03064.pdf |
| spellingShingle | Manzhurina Olga Shaposhnikov Ivan Yermakova Tatyana Bliznetsova Galina Parkhomenko Yulia Kotarev Vyacheslav Bryukhova Irina The study of the Profort probiotic use in the specific prevention of salmonellosis in calves E3S Web of Conferences |
| title | The study of the Profort probiotic use in the specific prevention of salmonellosis in calves |
| title_full | The study of the Profort probiotic use in the specific prevention of salmonellosis in calves |
| title_fullStr | The study of the Profort probiotic use in the specific prevention of salmonellosis in calves |
| title_full_unstemmed | The study of the Profort probiotic use in the specific prevention of salmonellosis in calves |
| title_short | The study of the Profort probiotic use in the specific prevention of salmonellosis in calves |
| title_sort | study of the profort probiotic use in the specific prevention of salmonellosis in calves |
| url | https://www.e3s-conferences.org/articles/e3sconf/pdf/2022/30/e3sconf_interagromash2022_03064.pdf |
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